Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19605877 | 0.90 | LMNA (0.66) | LMNAPOLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19403152 | 0.90 | LMNA (0.66) | LMNAPOLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL15363580 | 0.90 | LMNA (0.66) | LMNAPOLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL15694257 | 0.87 | ITGB3 (0.48) | LMNASMN1; SMN2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL26316648 | 0.84 | HRH3 (0.61) | LMNAPOLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL23977354 | 0.83 | LMNA (0.60) | LMNAPOLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL13336270 | 0.83 | KDM4E (0.43) | LMNAPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24115228 | 0.82 | LMNA (0.55) | LMNAPOLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL18807607 | 0.81 | LMNA (0.39) | LMNAPOLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5538919 | 0.78 | HSD17B10 (0.48) | SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3925952-B1 | PROSTATE-SPECIFIC MEMBRANE ANTIGEN TARGETED HIGH-AFFINITY AGENTS FOR ENDORADIOTHERAPY OF PROSTATE CANCER | UNIV JOHNS HOPKINS (US) | 2023-11-29 | — | — | EP | disclosed |