Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 3/20 | 0.41 |
| ▸ | CASP7 | P55210 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19586589 | 0.89 | PSMB5 (0.41) | PSMB5CASP1CASP3CASP7MMP2 | |
| SCHEMBL19586587 | 0.89 | PSMB5 (0.41) | PSMB5CASP1CASP3CASP7MMP2 | |
| SCHEMBL29530281 | 0.89 | PSMB5 (0.41) | PSMB5CASP1CASP3CASP7MMP2 | |
| SCHEMBL19605978 | 0.89 | CTSD (0.44) | CTSDCASP1CASP3CASP7MMP2 | |
| SCHEMBL29530391 | 0.86 | PSMB5 (0.52) | CTSDPSMB5MMP2MMP9MMP8 | |
| SCHEMBL22875711 | 0.81 | CTSD (0.44) | CTSDPSMB5CASP1CASP3CASP7 | |
| SCHEMBL21772503 | 0.80 | PSMB5 (0.56) | CTSDPSMB5MMP2MMP9MMP8 | |
| SCHEMBL19586109 | 0.80 | PSMB5 (0.56) | CTSDPSMB5MMP2MMP9MMP8 | |
| SCHEMBL19605943 | 0.77 | MMP2 (0.42) | MMP2MMP9MMP8CTSBKRAS | |
| SCHEMBL28563734 | 0.77 | CTSD (0.53) | CTSDPSMB5MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11859014-B2 | Peptidomimetics for the treatment of Norovirus infection | EMORY UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| WO-2017197377-A1 | PEPTIDOMIMETICS FOR THE TREATMENT OF NOROVIRUS INFECTION | EMORY UNIVERSITY (US) | 2017-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11859014-B2 | Peptidomimetics for the treatment of Norovirus infection | VIP, HAVCR2, NGLY1 | CTSD 868/4885PSMB5 1096/4885CASP1 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.