SCHEMBL29530391

SCHEMBL29530391

CCCCCCCCCCCC(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)OC

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PSMB5 P28074 3/20 0.52
▸ MMP9 P14780 2/20 0.51
▸ MMP8 P22894 2/20 0.51
▸ MMP2 P08253 1/20 0.51
▸ CTSD P07339 1/20 0.51
▸ CTSB P07858 1/20 0.47
▸ CTSK P43235 1/20 0.47
▸ MME P08473 1/20 0.46
▸ ACE P12821 1/20 0.46
▸ CPA1 P15085 1/20 0.46
▸ ACE2 Q9BYF1 1/20 0.46
▸ KRAS P01116 1/20 0.46
▸ MMP14 P50281 1/20 0.45
▸ ANPEP P15144 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21772503 0.91 PSMB5 (0.56) PSMB5MMP9MMP8MMP2CTSD
SCHEMBL19586109 0.91 PSMB5 (0.56) PSMB5MMP9MMP8MMP2CTSD
SCHEMBL29535660 0.86 CTSD (0.53) PSMB5MMP9MMP8MMP2CTSD
SCHEMBL28560400 0.86 CTSD (0.53) PSMB5MMP9MMP8MMP2CTSD
SCHEMBL28563734 0.86 CTSD (0.53) PSMB5MMP9MMP8MMP2CTSD
SCHEMBL28517814 0.86 CTSD (0.53) PSMB5MMP9MMP8MMP2CTSD
SCHEMBL19605979 0.86 CTSD (0.44) PSMB5MMP9MMP8MMP2CTSD
SCHEMBL28523691 0.85 CTSB (0.59) PSMB5MMP9MMP8MMP2CTSD
SCHEMBL29535481 0.85 CTSB (0.59) PSMB5MMP9MMP8MMP2CTSD
SCHEMBL19605957 0.84 TACR1 (0.55) PSMB5MMP9MMP8MMP2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3980400-B1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS UNIV EMORY (US) 2025-08-06 — — EP disclosed
US-12268723-B2 Peptidomimetics for the treatment of coronavirus and picorna virus infections EMORY UNIVERSITY (US) 2025-04-08 — — US disclosed
US-11859014-B2 Peptidomimetics for the treatment of Norovirus infection EMORY UNIVERSITY (US) 2024-01-02 — — US disclosed
US-20220273753-A1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS EMORY UNIVERSITY 2022-09-01 — — US disclosed
EP-3980400-A1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS Emory University (US) 2022-04-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11859014-B2 Peptidomimetics for the treatment of Norovirus infection VIP, HAVCR2, NGLY1 PSMB5 1096/4885MMP9 4036/4885MMP8 1845/4885
US-20220273753-A1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS ACE2, SARS1, VIP PSMB5 3646/4885MMP9 2357/4885MMP8 2376/4885
US-12268723-B2 Peptidomimetics for the treatment of coronavirus and picorna virus infections ACE2, SARS1, HAVCR2 PSMB5 3776/4885MMP9 2109/4885MMP8 2086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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