Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | BUB1 | O43683 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19128661 | 0.85 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1BCHEBUB1GPR119 | |
| SCHEMBL8315409 | 0.81 | TRIM24 (0.47) | BCHETRIM24TRIM33ALDH1A1L3MBTL1 | |
| SCHEMBL28274140 | 0.80 | BCHE (0.41) | HSP90AA1HSP90AB1BCHEBUB1GPR119 | |
| SCHEMBL17447201 | 0.79 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1BCHEBUB1ALDH1A1 | |
| SCHEMBL8377839 | 0.78 | ALDH1A1 (0.45) | BCHETRIM24TRIM33ALDH1A1GAA | |
| SCHEMBL163016 | 0.77 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1BCHEBUB1GPR119 | |
| SCHEMBL15417736 | 0.77 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1BCHEBUB1GPR119 | |
| SCHEMBL4916320 | 0.77 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1BCHEBUB1GPR119 | |
| SCHEMBL16881172 | 0.76 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1BCHEBUB1GPR119 | |
| SCHEMBL24914436 | 0.76 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1BCHEBUB1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112239468-B | Metal-free solvent-free synthesis of fused pyridine heterocycles and biomedical applications thereof | 印多尔印度理工学院 | 2025-05-27 | — | — | CN | disclosed |
| WO-2024010732-A1 | SMALL MOLECULE INHIBITORS OF GLUTAMINE TRANSPORTER ASCT2 AND METHODS OF USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-01-11 | — | — | WO | disclosed |
| WO-2023238683-A1 | NOVEL HETEROCYCLIC COMPOUND AND SALT THEREOF, AND LUMINESCENT SUBSTRATE COMPOSITION | 国立大学法人電気通信大学 | 2023-12-14 | — | — | WO | disclosed |
| US-11814366-B2 | Antiviral compounds and use thereof | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2023-11-14 | — | — | US | disclosed |
| EP-3765454-B1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | UNIV DEGLI STUDI DI SIENA (IT) | 2023-11-08 | — | — | EP | disclosed |
| EP-3512858-B1 | FUSED BICYCLIC INHIBITORS OF MENIN-MLL INTERACTION | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-08 | — | — | EP | disclosed |
| US-20230279019-A1 | BENZONORBORNADIENE DERIVATIVES AND REACTIONS THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2023-09-07 | — | — | US | disclosed |
| CN-109422755-B | Nitrogen-containing heterocyclic compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| US-11578074-B2 | Nitrogenous heterocyclic compound, preparation method, intermediate, composition, and application | Shanghai Pharmaceuticals Holding Cd., Ltd. (CN) | 2023-02-14 | — | — | US | disclosed |
| US-11560384-B2 | Benzonorbornadiene derivatives and reactions thereof | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2023-01-24 | — | — | US | disclosed |
| US-6504034-B2 | Cell antiproliferative agents; anticancer agents | HOFFMANN-LA ROCHE INC. | 2003-01-07 | — | — | US | disclosed |
| US-20020147343-A1 | Naphthostyrils | CHEN YI (US) | 2002-10-10 | — | — | US | disclosed |
| WO-2002059109-A2 | NAPHTHOSTYRIL DERIVATIVES AND THEIR USE AS INHIBITORS OF CYCLIN- DEPENDENT KINASES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-08-01 | — | — | WO | disclosed |
| US-6191145-B1 | ANTICOAGULANTS; ANTIINFLAMMATORY AGENTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-02-20 | — | — | US | disclosed |
| US-6066651-A | ANTITHROMBOTIC AGENTS BY VIRTUE OF THEIR ABILITY TO PREVENT PLATELET AGGREGATION | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-05-23 | — | — | US | disclosed |
| US-5891877-A | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR | XENOVA LIMITED (GB) | 1999-04-06 | — | — | US | disclosed |
| EP-0745070-A1 | PHARMACEUTICAL PIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1996-12-04 | — | — | EP | disclosed |
| US-5567726-A | SELECTIVE AGONISTS OF 5-HYDROXYTRYPTAMINE-LIKE RECEPTORS; USEFUL IN TREATMENT OF MIGRAINE AND ASSOCIATED DISORDERS | MERCK, SHARP & DOHME LTD. (GB) | 1996-10-22 | — | — | US | disclosed |
| WO-1995021832-A1 | PHARMACEUTICAL PIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1995-08-17 | — | — | WO | disclosed |
| WO-1994002477-A1 | IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814366-B2 | Antiviral compounds and use thereof | MAVS, EIF2AK2, SARS1 | HSP90AA1 1369/4885HSP90AB1 1324/4885BCHE 2325/4885 |
| US-20020147343-A1 | Naphthostyrils | CCNI, CDKL1, CDK2 | HSP90AA1 2543/4885HSP90AB1 2505/4885BCHE 3532/4885 |
| US-20230279019-A1 | BENZONORBORNADIENE DERIVATIVES AND REACTIONS THEREOF | CBR3, CBR1, CNR1 | HSP90AA1 3859/4885HSP90AB1 3403/4885BCHE 1299/4885 |
| US-11578074-B2 | Nitrogenous heterocyclic compound, preparation method, intermediate, composition, and application | ERBB2, EGFR, ERBB4 | HSP90AA1 2346/4885HSP90AB1 1692/4885BCHE 2407/4885 |
| US-11560384-B2 | Benzonorbornadiene derivatives and reactions thereof | CBR3, CBR1, CNR1 | HSP90AA1 3979/4885HSP90AB1 3582/4885BCHE 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.