Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LPO | P22079 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377839 | 0.82 | ALDH1A1 (0.45) | TRIM24TRIM33ALDH1A1GAALPO | |
| SCHEMBL1960653 | 0.81 | HSP90AA1 (0.44) | TRIM24TRIM33ALDH1A1GAACYP1A2 | |
| SCHEMBL21407436 | 0.79 | TRIM24 (0.52) | TRIM24TRIM33ALDH1A1GAACYP1A2 | |
| SCHEMBL7969238 | 0.77 | TRIM24 (0.40) | TRIM24TRIM33ALDH1A1GAACYP1A2 | |
| SCHEMBL7958548 | 0.77 | TRIM24 (0.40) | TRIM24TRIM33ALDH1A1GAACYP1A2 | |
| SCHEMBL22076913 | 0.76 | ATM (0.48) | TRIM24TRIM33ALDH1A1GAACYP1A2 | |
| SCHEMBL16552204 | 0.75 | TRIM24 (0.38) | TRIM24TRIM33ALDH1A1GAALPO | |
| SCHEMBL162288 | 0.75 | LPO (0.44) | ALDH1A1LPOL3MBTL1P2RX4ATM | |
| SCHEMBL28885007 | 0.75 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1GAACYP1A2 | |
| SCHEMBL10772523 | 0.74 | P2RX4 (0.49) | ALDH1A1L3MBTL1SMN1; SMN2P2RX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623619-B1 | PREPARATION METHOD OF ARENO[e]INDOLS | PHARMA MAR S A PHARMAR (ES) | 1999-02-03 | — | — | EP | disclosed |
| US-5631384-A | Areno [e]indols, preparation method and application as intermediates in the synthesis of products with antitumoral activity | PHARMA-MAR, S.A.-PHARMAR (ES) | 1997-05-20 | — | — | US | disclosed |
| US-5571927-A | Areno [E]indols, preparation method and application as intermediates in the synthesis of products with antitumoral activity | PHARMA-MAR, S.A.- PHARMAR (ES) | 1996-11-05 | — | — | US | disclosed |
| EP-0623619-A1 | NEW ARENO[e]INDOLS, PREPARATION METHOD AND APPLICATION AS INTERMEDIATES IN THE SYNTHESIS OF PRODUCTS WITH ANTITUMORAL ACTIVITY | PHARMA-MAR S.A.-PHARMAR (ES) | 1994-11-09 | — | — | EP | disclosed |