⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2992341 | 0.81 | — | — | |
| SCHEMBL5114255 | 0.80 | — | — | |
| SCHEMBL27843736 | 0.78 | — | — | |
| SCHEMBL27986820 | 0.77 | LMNA (0.52) | — | |
| SCHEMBL5577366 | 0.77 | ALDH1A1 (0.47) | — | |
| SCHEMBL26725021 | 0.76 | ALDH1A1 (0.41) | — | |
| SCHEMBL26725020 | 0.76 | ALDH1A1 (0.41) | — | |
| SCHEMBL8379654 | 0.74 | ALDH1A1 (0.39) | — | |
| SCHEMBL20636979 | 0.73 | — | — | |
| SCHEMBL2996964 | 0.73 | GABRP (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197051-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |