Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 7/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960687 | 1.00 | CYP3A4 (0.49) | CYP3A4CYP2D6PDE10AFAAHGABRA1 | |
| SCHEMBL1076091 | 0.92 | CYP3A4 (0.50) | CYP3A4CYP2D6PDE10AFAAHGABRA1 | |
| SCHEMBL1076089 | 0.92 | CYP3A4 (0.50) | CYP3A4CYP2D6PDE10AFAAHGABRA1 | |
| SCHEMBL1038541 | 0.91 | CYP3A4 (0.51) | CYP3A4CYP2D6FAAHGABRA1ADRA2C | |
| SCHEMBL1038543 | 0.91 | CYP3A4 (0.51) | CYP3A4CYP2D6FAAHGABRA1ADRA2C | |
| SCHEMBL1039475 | 0.91 | CYP3A4 (0.44) | CYP3A4CYP2D6FAAHGABRA1ADRA2C | |
| SCHEMBL1039472 | 0.91 | CYP3A4 (0.44) | CYP3A4CYP2D6FAAHGABRA1ADRA2C | |
| SCHEMBL1037355 | 0.91 | CYP3A4 (0.48) | CYP3A4CYP2D6FAAHHTR2AHTR2C | |
| SCHEMBL1037354 | 0.91 | CYP3A4 (0.48) | CYP3A4CYP2D6FAAHHTR2AHTR2C | |
| SCHEMBL1961916 | 0.90 | CYP3A4 (0.51) | CYP3A4CYP2D6FAAHGABRA1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144159-A1 | ETHER BENZYLIDENE PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | PFIZER INC | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144159-A1 | ETHER BENZYLIDENE PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | FAAH, FAAH2, PAH | CYP3A4 329/4885CYP2D6 382/4885PDE10A 1516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.