SCHEMBL19610232

SCHEMBL19610232

O=[N+]([O-])C(O)(Cc1ccccc1)[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP2C9 P11712 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.44
HIF1A Q16665 1/20 0.44
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CPA1 P15085 5/20 0.41
SLC6A2 P23975 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
MMP8 P22894 1/20 0.38
KCNA5 P22460 1/20 0.37
AKR1B1 P15121 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8331176 0.83 FDPS (0.47) FDPSCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL4371898 0.79 SLC6A2 (0.48) FDPSCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL1828129 0.78 SMN1; SMN2 (0.42) FDPSCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL30331135 0.78 FDPS (0.46) FDPSCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL9617912 0.76 SMN1; SMN2 (0.50) FDPSCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL10717351 0.76 SMN1; SMN2 (0.50) FDPSCYP1A2CYP2C19CYP2C9SMN1; SMN2
Phenol SCHEMBL28311359 0.76 FNTA (0.42) FDPSCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL3293297 0.75 SLC6A2 (0.48) FDPSCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL3202580 0.73 CYP1A2 (0.45) FDPSCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL14935688 0.73 SMN1; SMN2 (0.56) FDPSCYP1A2CYP2C19CYP2C9SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3246307-A1 METHOD FOR PRODUCING DIAMINE PRECURSOR COMPOUND Nissan Chemical Industries, Ltd. (JP) 2017-11-22 EP disclosed