SCHEMBL14935688

SCHEMBL14935688

N[C@](Cc1ccccc1)(C(=O)O)[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.56
HIF1A Q16665 1/20 0.56
SLC6A2 P23975 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ARG1 P05089 1/20 0.42
ARG2 P78540 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CPA1 P15085 3/20 0.40
BLM P54132 1/20 0.39
KEAP1 Q14145 1/20 0.38
FDPS P14324 1/20 0.38
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
CYP2C19 P33261 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C9 P11712 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28243868 1.00 SMN1; SMN2 (0.56) SMN1; SMN2HIF1ASLC6A2TAAR1ARG1
SCHEMBL4362988 1.00 SMN1; SMN2 (0.56) SMN1; SMN2HIF1ASLC6A2TAAR1ARG1
SCHEMBL7795287 0.86 SMN1; SMN2 (0.49) SMN1; SMN2HIF1ASLC6A2TAAR1ARG1
SCHEMBL3891306 0.86 BLM (0.56) SMN1; SMN2HIF1ABLMCYP1A2CYP3A4
SCHEMBL3891311 0.86 BLM (0.56) SMN1; SMN2HIF1ABLMCYP1A2CYP3A4
SCHEMBL10717351 0.78 SMN1; SMN2 (0.50) SMN1; SMN2HIF1AARG1ARG2CES2
SCHEMBL9617912 0.78 SMN1; SMN2 (0.50) SMN1; SMN2HIF1AARG1ARG2CES2
SCHEMBL1828129 0.77 SMN1; SMN2 (0.42) SMN1; SMN2HIF1ASLC6A2TAAR1CES2
SCHEMBL28360703 0.75 SMN1; SMN2 (0.47) SMN1; SMN2HIF1AARG1ARG2CES2
SCHEMBL27548994 0.75 SMN1; SMN2 (0.38) SMN1; SMN2HIF1ASLC6A2TAAR1ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240008483-A1 COMPOSITION FOR MOLD REMEDIATION MOLD GUARD INC. (CA) 2024-01-11 US claimed
CN-116997648-A Composition for mould repair 霉菌防护有限公司 2023-11-03 CN claimed
EP-4244364-A1 COMPOSITION FOR MOLD REMEDIATION Mold Guard Inc. (CA) 2023-09-20 EP claimed
WO-2022104023-A1 COMPOSITION FOR MOLD REMEDIATION MOLD GUARD INC. (CA) 2022-05-19 WO claimed
US-20260083834-A1 CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY TRANSFERT PLUS LP (CA) 2026-03-26 US disclosed
US-20250367300-A1 Nanomaterial and Methods of Use Thereof UNIVERSITY OF CONNECTICUT (US) 2025-12-04 US disclosed
US-20250302971-A1 Therapeutic Nanomaterials UNIV CONNECTICUT (US) 2025-10-02 US disclosed
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2025-10-02 US disclosed
US-20250229081-A1 NANOMATERIAL COATED ELECTRODE AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT 2025-07-17 US disclosed
EP-4584301-A1 CSGA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY Transfert Plus, Limited Partnership (CA) 2025-07-16 EP disclosed
EP-4578867-A1 CYCLIC PEPTIDE OR SALT THEREOF AND MDMX INHIBITOR FUJIFILM Corporation (JP) 2025-07-02 EP disclosed
EP-4578868-A1 CYCLIC PEPTIDE OR SALT THEREOF, AND MDMX INHIBITOR FUJIFILM Corporation (JP) 2025-07-02 EP disclosed
US-20150051155-A1 PEPTIDOMIMETIC MACROCYCLES HOFFMANN-LA ROCHE, INC. 2015-02-19 US disclosed
US-8927500-B2 Peptidomimetic macrocycles AILERON THERAPEUTICS, INC. (US) 2015-01-06 US disclosed
CN-104159595-A Peptidomimetic macrocycles AILERON THERAPEUTICS INC 2014-11-19 CN disclosed
CN-104144695-A Triazole-and thioether-crosslinked peptidomimetic macrocycles AILERON THERAPEUTICS INC 2014-11-12 CN disclosed
CN-104039342-A Peptidomimetic macrocycles AILERON THERAPEUTICS INC 2014-09-10 CN disclosed
US-20130274205-A1 PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. 2013-10-17 US disclosed
US-20130210745-A1 TRIAZOLE-CROSSLINKED AND THIOETHER-CROSSLINKED PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. (US) 2013-08-15 US disclosed
US-20130123169-A1 PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. (US) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302971-A1 Therapeutic Nanomaterials TIE1, TEKT1, POLRMT SMN1; SMN2 2104/4885HIF1A 1523/4885SLC6A2 999/4885
US-20250367300-A1 Nanomaterial and Methods of Use Thereof EPCAM, CD47, JAK2 SMN1; SMN2 1218/4885HIF1A 3475/4885SLC6A2 491/4885
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF JAK2, JAK1, CHMP4B SMN1; SMN2 84/4885HIF1A 2308/4885SLC6A2 104/4885
US-20150051155-A1 PEPTIDOMIMETIC MACROCYCLES TP53, MDM2, MDM4 SMN1; SMN2 2468/4885HIF1A 2561/4885SLC6A2 4884/4885
US-20260083834-A1 CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY VSIG8, MICA, CD74 SMN1; SMN2 2636/4885HIF1A 3245/4885SLC6A2 3293/4885
US-20130123169-A1 PEPTIDOMIMETIC MACROCYCLES GHRHR, GHSR, GHITM SMN1; SMN2 2636/4885HIF1A 781/4885SLC6A2 4309/4885
US-20130210745-A1 TRIAZOLE-CROSSLINKED AND THIOETHER-CROSSLINKED PEPTIDOMIMETIC MACROCYCLES IL33, TPR, CDC37 SMN1; SMN2 3907/4885HIF1A 1402/4885SLC6A2 4812/4885
US-20130274205-A1 PEPTIDOMIMETIC MACROCYCLES PROKR1, GLP1R, PROKR2 SMN1; SMN2 1167/4885HIF1A 1052/4885SLC6A2 4788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.