SCHEMBL19610355

SCHEMBL19610355

COc1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 1/20 0.36
ALDH1A1 P00352 4/20 0.35
TSHR P16473 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
EGFR P00533 2/20 0.34
UCHL1 P09936 1/20 0.34
LPL P06858 3/20 0.33
LIPG Q9Y5X9 3/20 0.33
KDM4E B2RXH2 2/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CA7 P43166 1/20 0.32
JAK2 O60674 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23888269 0.85 CSF1R (0.34) CSF1RALDH1A1TSHRNPSR1EGFR
SCHEMBL16760393 0.85 CSF1R (0.34) CSF1RALDH1A1TSHREGFRUCHL1
SCHEMBL16815655 0.85 EGFR (0.37) CSF1RALDH1A1KMT2ANPSR1EGFR
SCHEMBL29869496 0.85 CSF1R (0.34) CSF1RALDH1A1TSHRNPSR1EGFR
SCHEMBL12533726 0.85 EGFR (0.37) CSF1RALDH1A1NPSR1SMN1; SMN2EGFR
SCHEMBL12703333 0.84 LPL (0.42) LPLLIPGCA1CA2CA9
SCHEMBL1870652 0.84 JAK2 (0.38) CSF1RALDH1A1TSHRMEN1KMT2A
SCHEMBL16241628 0.81 ERN1 (0.36) CSF1RALDH1A1TSHRNPSR1SMN1; SMN2
SCHEMBL30971294 0.81 UCHL1 (0.33) CSF1RUCHL1LPLLIPGCA1
SCHEMBL20508307 0.79 LPL (0.40) CSF1REGFRUCHL1LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3246314-B1 CARBAMATE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2020-04-08 EP disclosed
US-10383333-B2 Carbamate compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-08-20 US disclosed
US-20180014539-A1 CARBAMATE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-18 US disclosed
EP-3246314-A1 CARBAMATE COMPOUND AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2017-11-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180014539-A1 CARBAMATE COMPOUND AND USE THEREOF C9, C5, C1S CSF1R 1292/4885ALDH1A1 3901/4885TSHR 380/4885
US-10383333-B2 Carbamate compound and use thereof C9, C5, C1S CSF1R 1292/4885ALDH1A1 3901/4885TSHR 380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.