Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19610490 | 0.80 | CA1 (0.46) | SRD5A2THRATHRBKDM4EMEN1 | |
| SCHEMBL16860678 | 0.79 | GLRA1 (0.79) | GLRA1LMNAHPGDSRD5A2KDM4E | |
| SCHEMBL16860746 | 0.77 | GLRA1 (1.00) | GLRA1LMNAHPGDTHRATHRB | |
| SCHEMBL6036279 | 0.76 | GLRA1 (0.54) | GLRA1LMNAHPGDFFAR1THRA | |
| SCHEMBL20681207 | 0.75 | ACMSD (0.44) | HPGDPTGDR2KDM4E | |
| SCHEMBL30791048 | 0.75 | ACMSD (0.44) | HPGDPTGDR2KDM4E | |
| SCHEMBL16785954 | 0.75 | GLRA1 (0.63) | GLRA1LMNAHPGDMEN1KMT2A | |
| SCHEMBL4897760 | 0.74 | THRB (0.54) | GLRA1FFAR1THRATHRB | |
| SCHEMBL25138966 | 0.74 | PTGER1 (0.51) | GLRA1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL31419968 | 0.74 | GLRA1 (0.62) | GLRA1LMNAHPGDTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246022-A1 | THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | Xi'an Libang Pharmaceutical Co., Ltd (CN) | 2017-11-22 | — | — | EP | claimed |
| US-20200179302-A1 | USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2020-06-11 | — | — | US | disclosed |
| US-10329243-B2 | Biphenyl derivative and uses thereof | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2019-06-25 | — | — | US | disclosed |
| US-20180185299-A1 | THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-07-05 | — | — | US | disclosed |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-05-24 | — | — | US | disclosed |
| EP-3246022-A1 | THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | Xi'an Libang Pharmaceutical Co., Ltd (CN) | 2017-11-22 | — | — | EP | disclosed |
| EP-3246304-A2 | DIPHENYL DERIVATIVE AND USES THEREOF | Xi'an Libang Pharmaceutical Co., Ltd (CN) | 2017-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200179302-A1 | USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | PTGER3, PTGES3, CYP24A1 | GLRA1 3133/4885LMNA 1953/4885HPGD 161/4885 |
| US-10329243-B2 | Biphenyl derivative and uses thereof | PPARD, PCSK9, UGT2B7 | GLRA1 4174/4885LMNA 1295/4885HPGD 1580/4885 |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | PPARD, DPP3, DPP7 | GLRA1 4599/4885LMNA 1537/4885HPGD 804/4885 |
| US-20180185299-A1 | THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | PTGER3, CYP24A1, PTGES3 | GLRA1 3356/4885LMNA 1690/4885HPGD 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.