Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 6/20 | 0.38 |
| ▸ | THRB | P10828 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19610475 | 0.93 | CA1 (0.61) | CA1CA2GAATHRATHRB | |
| SCHEMBL20699064 | 0.86 | KDM4E (0.44) | KDM4EGAAFABP3FABP4THRA | |
| SCHEMBL8137246 | 0.86 | FABP3 (0.57) | KDM4EGAAFABP3FABP4THRA | |
| SCHEMBL20698934 | 0.85 | AURKA (0.44) | KDM4EGAATHRATHRBMAPT | |
| SCHEMBL19475246 | 0.84 | GABRA1 (0.50) | KDM4EGAAFABP3FABP4THRA | |
| SCHEMBL20681232 | 0.84 | GABRA1 (0.50) | KDM4EGAAFABP3FABP4THRA | |
| SCHEMBL19475203 | 0.84 | NLRP3 (0.41) | KDM4EGAAFABP3FABP4THRA | |
| SCHEMBL20698932 | 0.84 | LMNA (0.42) | THRATHRBPOLBAKR1B1MEN1 | |
| SCHEMBL30791048 | 0.84 | ACMSD (0.44) | KDM4EGAAALDH1A1 | |
| SCHEMBL20681207 | 0.84 | ACMSD (0.44) | KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246022-A1 | THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | Xi'an Libang Pharmaceutical Co., Ltd (CN) | 2017-11-22 | — | — | EP | claimed |
| US-20200179302-A1 | USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2020-06-11 | — | — | US | disclosed |
| US-20180185299-A1 | THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-07-05 | — | — | US | disclosed |
| EP-3246022-A1 | THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | Xi'an Libang Pharmaceutical Co., Ltd (CN) | 2017-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200179302-A1 | USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | PTGER3, PTGES3, CYP24A1 | CA1 231/4885CA2 333/4885KDM4E 2139/4885 |
| US-20180185299-A1 | THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | PTGER3, CYP24A1, PTGES3 | CA1 171/4885CA2 279/4885KDM4E 1841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.