Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263730 | 0.82 | PTGES (0.68) | PTGESMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL5451796 | 0.80 | ALDH1A1 (0.70) | PTGESMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL25709829 | 0.79 | PTGES (0.66) | PTGESMAPTALDH1A1RAB9ASMN1; SMN2 | |
| Etocarlide SCHEMBL2439224 | 0.78 | MAPT (0.89) | PTGESMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28999618 | 0.78 | PTGES (0.63) | PTGESMAPTMAPK1GAAL3MBTL1 | |
| SCHEMBL23302979 | 0.77 | PTGES (0.62) | PTGESMAPTALDH1A1RAB9AKDM4E | |
| Etocarlide SCHEMBL359440 | 0.77 | MAPT (0.96) | PTGESMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1263398 | 0.77 | PTGES (0.62) | PTGESMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL11001964 | 0.77 | PTGES (0.62) | PTGESMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL11000930 | 0.77 | PTGES (0.62) | PTGESMAPTALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106810469-B | A kind of device and its production method of continuous production thiofide diphenylguanidine | 山东尚舜化工有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-109304079-A | The recyclable device and method of tail gas for rubber accelerator M | 山东众瑞新材料科技有限公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109256587-A | Lithium metal secondary battery electrolyte and the lithium metal secondary battery for using the electrolyte | 青海泰丰先行锂能科技有限公司 | 2019-01-22 | — | — | CN | claimed |
| CN-108641603-A | A kind of polishing powder recovery process | 永嘉立豪环保科技有限公司 | 2018-10-12 | — | — | CN | claimed |
| CN-107827781-A | The production technology and equipments of continuous production diphenylguanidine | 山东尚舜化工有限公司 | 2018-03-23 | — | — | CN | claimed |
| CN-206751706-U | A kind of device of continuous production thiofide diphenylguanidine | 山东尚舜化工有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-106810469-A | The device and its production method of a kind of continuous production thiofide diphenylguanidine | 山东尚舜化工有限公司 | 2017-06-09 | — | — | CN | claimed |
| CN-104024318-B | Curable compositions based on the nitrile rubber containing epoxide group | 朗盛德国有限责任公司 | 2016-10-26 | — | — | CN | claimed |
| CN-105916376-A | Agrochemical composition | 农作物智力有限公司 | 2016-08-31 | — | — | CN | claimed |
| CN-105348149-A | Method for improving quality of diphenylguanidine product | SHANDONG SUNSINE CHEMICAL CO LTD | 2016-02-24 | — | — | CN | claimed |
| CN-203648513-U | Automatic temperature control system for diphenylthiourea synthetic reaction | TIANJIN YIHUA CHEMICAL CO LTD | 2014-06-18 | — | — | CN | claimed |
| CN-103551256-A | Activating agent for use in floatation of silver in zinc hydrometallurgy acid leaching pulp | ZHUZHOU XIANGQI TECHNOLOGY DEV CO LTD | 2014-02-05 | — | — | CN | claimed |
| CN-103556151-A | Chemical milling solution and chemical milling method of gamma-titanium aluminum-based intermetallic compound | INST METAL RES CHINESE ACAD SC | 2014-02-05 | — | — | CN | claimed |
| CN-102426204-B | Method for analyzing content of rubber accelerator thiocarbanilide | KEMAI CHEMICAL CO LTD | 2013-08-14 | — | — | CN | claimed |
| CN-102426204-A | Method for analyzing content of rubber accelerator thiocarbanilide | KEMAI CHEMICAL CO LTD | 2012-04-25 | — | — | CN | claimed |
| US-20110142956-A1 | USE OF A PDE 5 INHIBITOR FOR TREATING AND PREVENTING HYPOPIGMENTARY DISORDERS | PEUKER HEIDEMARIE | 2011-06-16 | — | — | US | claimed |
| US-20080051408-A1 | Use of a Pde 5 Inhibitor for Treating and Preventing Hypopigmentary Disorders | SWITCH BIOTECH, LLC | 2008-02-28 | — | — | US | claimed |
| EP-1759700-A1 | Use of a PDE5 inhibitor for treating and preventing hypopigmentary disorders | Switch Biotech Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | claimed |
| WO-2006018088-A1 | USE OF A PDE 5 INHIBITOR FOR TREATING AND PREVENTING HYPOPIGMENTARY DISORDERS | SWITCH BIOTECH AG (DE) | 2006-02-23 | — | — | WO | claimed |
| WO-2004096222-A1 | USE OF 1-(5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE, ITS ACTIVE METABOLITES, ISOMERS AND SALTS FOR TREATING AND PREVENTING HYPOPIGMENTARY DISORDERS | SWITCH BIOTECH AG (DE) | 2004-11-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110142956-A1 | USE OF A PDE 5 INHIBITOR FOR TREATING AND PREVENTING HYPOPIGMENTARY DISORDERS | PDE5A, PDE12, PDE2A | PTGES 1933/4885MAPT 1589/4885ALDH1A1 342/4885 |
| US-20080051408-A1 | Use of a Pde 5 Inhibitor for Treating and Preventing Hypopigmentary Disorders | PDE5A, PDE2A, PDE3A | PTGES 2538/4885MAPT 989/4885ALDH1A1 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.