SCHEMBL5451796

SCHEMBL5451796

CN(C)c1ccc(NC(=S)Nc2ccc(N(C)C)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.70
MAPT P10636 8/20 0.70
GAA P10253 7/20 0.70
SMN1; SMN2 Q16637 6/20 0.70
KMT2A Q03164 3/20 0.70
PTGES O14684 1/20 0.65
RAB9A P51151 4/20 0.58
MEN1 O00255 2/20 0.58
KDM4E B2RXH2 3/20 0.55
HTT P42858 3/20 0.55
THRB P10828 2/20 0.55
MAPK1 P28482 2/20 0.55
NPC1 O15118 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
LMNA P02545 2/20 0.53
TP53 P04637 2/20 0.53
HPGD P15428 2/20 0.53
HSD17B10 Q99714 2/20 0.53
MITF O75030 1/20 0.53
APP P05067 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2513608 0.92 ALDH1A1 (0.65) ALDH1A1MAPTGAASMN1; SMN2KMT2A
SCHEMBL11543444 0.90 ALDH1A1 (0.63) ALDH1A1MAPTGAASMN1; SMN2KMT2A
SCHEMBL14386119 0.85 GAA (0.69) ALDH1A1MAPTGAASMN1; SMN2KMT2A
SCHEMBL863314 0.84 MAPT (0.74) ALDH1A1MAPTGAASMN1; SMN2KMT2A
SCHEMBL5448340 0.83 ALDH1A1 (0.67) ALDH1A1MAPTGAASMN1; SMN2KMT2A
SCHEMBL6926083 0.83 MAPT (1.00) ALDH1A1MAPTGAASMN1; SMN2KMT2A
SCHEMBL9725156 0.83 MAPT (0.78) ALDH1A1MAPTGAASMN1; SMN2KMT2A
SCHEMBL14385673 0.82 GAA (0.65) ALDH1A1MAPTGAASMN1; SMN2KMT2A
Thiambutosine SCHEMBL1961184 0.80 PTGES (1.00) ALDH1A1MAPTGAASMN1; SMN2KMT2A
SCHEMBL14358886 0.80 MAPT (0.56) ALDH1A1MAPTGAASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4421344-A THIOUREA, AND ZINC OXIDE OR HYDROXIDE TO PREVENT FADING OJI PAPER CO., LTD. (JP) 1983-12-20 US claimed
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed
US-4421344-A THIOUREA, AND ZINC OXIDE OR HYDROXIDE TO PREVENT FADING OJI PAPER CO., LTD. (JP) 1983-12-20 US disclosed
US-4035244-A Electric recording process MITA INDUSTRIAL COMPANY LIMITED (JA) 1977-07-12 US disclosed