Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356625 | 0.98 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSLC6A2 | |
| SCHEMBL15627215 | 0.98 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSLC6A2 | |
| SCHEMBL6477452 | 0.98 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSLC6A2 | |
| SCHEMBL4541049 | 0.98 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSLC6A2 | |
| SCHEMBL15627217 | 0.98 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSLC6A2 | |
| SCHEMBL15627216 | 0.98 | SLC22A6 (0.52) | SLC22A6GABRR1LMNAMAPTSLC6A2 | |
| SCHEMBL9730926 | 0.96 | SLC22A6 (0.50) | SLC22A6GABRR1LMNAMAPTSLC6A2 | |
| SCHEMBL30645407 | 0.96 | SLC22A6 (0.50) | SLC22A6GABRR1LMNAMAPTSLC6A2 | |
| SCHEMBL22472213 | 0.82 | SLC22A6 (0.38) | SLC22A6GABRR1LMNAMAPTCYP2D6 | |
| SCHEMBL22472215 | 0.82 | SLC22A6 (0.38) | SLC22A6GABRR1LMNAMAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230817-B | The preparation method of 3,5-dihydroxy heptyl-6-gadoleic acid derivatives | 南京欧信医药技术有限公司 | 2016-09-14 | — | — | CN | disclosed |
| US-8497370-B2 | Processes for preparing amine salts of sildenafil-analogues and use thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-07-30 | — | — | US | disclosed |
| US-8470805-B2 | Processes for preparing piperazinium salts of KMUP and use thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-06-25 | — | — | US | disclosed |
| US-20120108604-A1 | PROCESSES FOR PREPARING AMINE SALTS OF SILDENAFIL-ANALOGUES AND USE THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-05-03 | — | — | US | disclosed |
| US-20110136767-A1 | PROCESSES FOR PREPARING PIPERAZINIUM SALTS OF KMUP AND USE THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-06-09 | — | — | US | disclosed |
| EP-1539711-A1 | PROCESS FOR PREPARING THE CALCIUM SALT OF ROSUVASTATIN | AstraZeneca UK Limited (GB) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004014872-A1 | PROCESS FOR PREPARING THE CALCIUM SALT OF ROSUVASTATIN | ASTRAZENECA UK LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136767-A1 | PROCESSES FOR PREPARING PIPERAZINIUM SALTS OF KMUP AND USE THEREOF | U2SURP, RRP15, KYNU | SLC22A6 2097/4885GABRR1 267/4885LMNA 2741/4885 |
| US-20120108604-A1 | PROCESSES FOR PREPARING AMINE SALTS OF SILDENAFIL-ANALOGUES AND USE THEREOF | PDE3A, PDE5A, PDE3B | SLC22A6 2189/4885GABRR1 935/4885LMNA 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.