SCHEMBL19612347

SCHEMBL19612347

COc1c(Cl)cc2ccccc2c1OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPK1 P28482 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ERN1 O75460 1/20 0.47
POLB P06746 1/20 0.44
HPGD P15428 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30577423 0.85 ERN1 (0.47) ALDH1A1KDM4EMAPK1SMN1; SMN2ERN1
SCHEMBL30949367 0.81 ALDH1A1 (0.67) ALDH1A1KDM4EMAPK1SMN1; SMN2ERN1
SCHEMBL599396 0.81 ALDH1A1 (0.67) ALDH1A1KDM4EMAPK1SMN1; SMN2ERN1
SCHEMBL19612332 0.79 MAPT (0.40) ALDH1A1KDM4EMAPK1SMN1; SMN2ERN1
SCHEMBL25185170 0.79 ERN1 (0.48) ALDH1A1KDM4EMAPK1SMN1; SMN2ERN1
SCHEMBL19612580 0.78 ALDH1A1 (0.50) ALDH1A1KDM4EMAPK1SMN1; SMN2ERN1
SCHEMBL2889415 0.78 MAOA (0.58) ALDH1A1KDM4EMAPK1SMN1; SMN2ERN1
SCHEMBL29227832 0.76 ALDH1A1 (0.48) ALDH1A1KDM4EMAPK1SMN1; SMN2ERN1
SCHEMBL8976429 0.76 ALDH1A1 (0.48) ALDH1A1KDM4EMAPK1SMN1; SMN2ERN1
SCHEMBL27423013 0.76 MAOA (0.56) ALDH1A1KDM4EMAPK1SMN1; SMN2ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170336728-A1 ULTRAVIOLET CURABLE LIQUID COMPOSITION, ULTRAVIOLET CURING INKJET INK, ULTRAVIOLET CURING WET ELECTROPHOTOGRAPHIC LIQUID DEVELOPER, ULTRAVIOLET CURING ELECTROSTATIC INKJET INK, AND IMAGE FORMING METHOD USING THEREOF CANON KABUSHIKI KAISHA (JP) 2017-11-23 US disclosed
CN-107108774-A Ultra-violet solidified fluid composition, the uv-curing type ink jet ink using it, ultraviolet hardening wet type electrophotographic liquid developer, ultraviolet hardening electrostatic inkjet ink and image forming method 佳能株式会社 2017-08-29 CN disclosed