SCHEMBL19612425

SCHEMBL19612425

c1ccc(COc2cccc(Oc3ccccc3)c2OCc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.55
MAPK1 P28482 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
HTR1A P08908 7/20 0.49
ADRA1D P25100 5/20 0.49
ADRA1A P35348 5/20 0.49
ADRA1B P35368 5/20 0.49
DRD2 P14416 2/20 0.47
ABCB1 P08183 1/20 0.47
MAOB P27338 4/20 0.46
LIPE Q05469 1/20 0.46
LTA4H P09960 1/20 0.45
MAPK14 Q16539 1/20 0.45
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
BCHE P06276 1/20 0.44
ALPG P10696 1/20 0.44
PTK2B Q14289 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19612273 0.89 MAPT (0.58) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL6215213 0.89 MAPT (0.67) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL19612324 0.84 MAPT (0.46) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL19612297 0.83 MAPT (0.45) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL28941896 0.81 HTR1A (0.57) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL18623128 0.80 HTR1A (0.68) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL19612234 0.79 PTGES (0.47) HTR1AADRA1DADRA1AADRA1B
SCHEMBL16632680 0.78 KMT2A (0.54) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL23041327 0.77 MAPT (0.58) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL19612226 0.77 ALOX5 (0.44) MAPTMAPK1TDP1L3MBTL1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170336728-A1 ULTRAVIOLET CURABLE LIQUID COMPOSITION, ULTRAVIOLET CURING INKJET INK, ULTRAVIOLET CURING WET ELECTROPHOTOGRAPHIC LIQUID DEVELOPER, ULTRAVIOLET CURING ELECTROSTATIC INKJET INK, AND IMAGE FORMING METHOD USING THEREOF CANON KABUSHIKI KAISHA (JP) 2017-11-23 US disclosed