SCHEMBL1961341

SCHEMBL1961341

CCOC(=O)c1ccc(COc2ccc(/N=N/c3ccc(/N=N/c4ccccc4)c4ccccc34)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.53
PPARD Q03181 1/20 0.53
PPARA Q07869 1/20 0.53
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
SMN1; SMN2 Q16637 6/20 0.46
MAPT P10636 4/20 0.46
RAB9A P51151 4/20 0.46
ALDH1A1 P00352 2/20 0.46
HTT P42858 2/20 0.46
GAA P10253 1/20 0.46
NPC1 O15118 2/20 0.45
MAOB P27338 1/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1961343 1.00 PPARG (0.53) PPARGPPARDPPARARXRARXRB
SCHEMBL1929061 0.86 NR4A2 (0.61) PPARGPPARDPPARARXRARXRB
SCHEMBL1929060 0.86 NR4A2 (0.61) PPARGPPARDPPARARXRARXRB
SCHEMBL340618 0.81 MAOB (0.67) PPARGRXRARXRBSMN1; SMN2MAPT
SCHEMBL11602002 0.81 SMN1; SMN2 (0.61) RXRARXRBSMN1; SMN2MAPTRAB9A
SCHEMBL12070544 0.80 RAB9A (0.52) SMN1; SMN2MAPTRAB9AALDH1A1GAA
SCHEMBL29042748 0.80 RXRA (0.47) PPARGPPARDPPARARXRARXRB
SCHEMBL18821735 0.79 RAB9A (0.67) SMN1; SMN2MAPTRAB9AALDH1A1GAA
SCHEMBL11888418 0.79 RAB9A (0.67) SMN1; SMN2MAPTRAB9AALDH1A1GAA
SCHEMBL12071728 0.79 MAPT (0.55) MAPTRAB9AALDH1A1NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590220-B2 Photoalignment materials having improved adhesion TRANSITIONS OPTICAL, INC. (US) 2020-03-17 US disclosed
US-20170037173-A1 Photoalignment Materials Having Improved Adhesion TRANSITIONS OPTICAL, INC. 2017-02-09 US disclosed
US-9475901-B2 Photoalignment materials having improved adhesion TRANSITIONS OPTICAL, INC. (US) 2016-10-25 US disclosed
EP-2510023-B1 PHOTOALIGNMENT MATERIALS HAVING IMPROVED ADHESION TRANSITIONS OPTICAL INC (US) 2013-09-11 EP disclosed
EP-2510023-A1 PHOTOALIGNMENT MATERIALS HAVING IMPROVED ADHESION Transitions Optical, Inc. (US) 2012-10-17 EP disclosed
CN-102695732-A Photoalignment materials having improved adhesion TRANSITIONS OPTICAL INC 2012-09-26 CN disclosed
WO-2011071794-A1 PHOTOALIGNMENT MATERIALS HAVING IMPROVED ADHESION TRANSITIONS OPTICAL, INC. (US) 2011-06-16 WO disclosed
US-20110135850-A1 PHOTOALIGNMENT MATERIALS HAVING IMPROVED ADHESION TRANSITIONS OPTICAL, INC. (US) 2011-06-09 US disclosed