1,2-Dichloroethane

1,2-Dichloroethane

SCHEMBL19614540

CC(Cl)Cl.CC(F)Cl.ClCCCl

nearest known ligand 0.46

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 3/20 0.46
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dichloroethane SCHEMBL28875111 0.88 TSHR (0.60) ALDH1A1TSHRMEN1KMT2AMAPK1
1,2-Dichloroethane SCHEMBL36872 0.88
1,2-Dichloroethane SCHEMBL19614542 0.81 ALDH1A1 (0.43) ALDH1A1TSHRMEN1KMT2A
1,2-Dichloroethane SCHEMBL9332177 0.79
SCHEMBL62010 0.78
1,2,3-Trichloropropane SCHEMBL16593659 0.74 TSHR (0.42) ALDH1A1TSHRMAPK1
SCHEMBL9332165 0.74
Methylene Chloride SCHEMBL7463180 0.74 ALDH1A1 (0.67) ALDH1A1TSHRMEN1KMT2AMAPK1
SCHEMBL8430070 0.74
Ammonia Solution, Strong SCHEMBL3289188 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170333941-A1 HIGH ENERGY EFFICIENCY PHASE CHANGE DEVICE USING CONVEX SURFACE FEATURES U.S. DEPARTMENT OF ENERGY 2017-11-23 US claimed
US-20170333941-A1 HIGH ENERGY EFFICIENCY PHASE CHANGE DEVICE USING CONVEX SURFACE FEATURES U.S. DEPARTMENT OF ENERGY 2017-11-23 US disclosed