1,2-Dichloroethane

1,2-Dichloroethane

SCHEMBL28875111

CC(Cl)Cl.CC(Cl)Cl.ClCCCl.ClCCCl

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.60
ALDH1A1 P00352 4/20 0.60
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dichloroethane SCHEMBL36872 1.00
1,2-Dichloroethane SCHEMBL19614540 0.88 ALDH1A1 (0.46) TSHRALDH1A1MEN1KMT2AMAPK1
1,2-Dichloroethane SCHEMBL19614542 0.84 ALDH1A1 (0.43) TSHRALDH1A1MEN1KMT2A
Methylene Chloride SCHEMBL700799 0.84
Methylene Chloride SCHEMBL7463180 0.84 ALDH1A1 (0.67) TSHRALDH1A1MEN1KMT2AMAPK1
1,2-Dichloroethane SCHEMBL8201807 0.82
Hexane SCHEMBL28835345 0.82 TSHR (0.56) TSHRALDH1A1TDP1
Ethyl Chloride SCHEMBL11811185 0.80
1,2-Dichloroethane SCHEMBL5313391 0.79 ALDH1A1 (0.38) TSHRALDH1A1
Chloroform SCHEMBL1194194 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110128295-A A kind of production technology based on micro- reaction synthesis chloro- 5- nitrobenzonitrile of 2- 浙江长华科技股份有限公司 2019-08-16 CN disclosed
CN-110041228-A A kind of o-chloro benzonitrile nitration processes 浙江长华科技股份有限公司 2019-07-23 CN disclosed
CN-109503630-A A kind of preparation method of Desacetylcefotaxime 河北合佳医药科技集团股份有限公司 2019-03-22 CN disclosed