Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL700799 | 1.00 | — | — | |
| 1,2-Dichloroethane SCHEMBL28875111 | 0.84 | TSHR (0.60) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| 1,2-Dichloroethane SCHEMBL36872 | 0.84 | — | — | |
| Ethyl Chloride SCHEMBL11811185 | 0.84 | — | — | |
| Methylene Chloride SCHEMBL29210337 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1 | |
| Trichloroethane SCHEMBL28756506 | 0.83 | TSHR (0.46) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL5438089 | 0.82 | — | — | |
| SCHEMBL5728116 | 0.82 | — | — | |
| SCHEMBL126 | 0.82 | — | — | |
| SCHEMBL11523834 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802915-B1 | CAMPTOTHECIN DERIVATIVES AND ITS MANUFACTURING METHOD | CHONG KUN DANG CORP (KR) | 2002-12-04 | — | — | EP | disclosed |
| EP-0802915-A1 | CAMPTOTHECIN DERIVATIVES AND ITS MANUFACTURING METHOD | CHONG KUN DANG CORP (KR) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021666-A1 | CAMPTOTHECIN DERIVATIVES AND ITS MANUFACTURING METHOD | CHONG KUN DANG CORPORATION (KR) | 1996-07-18 | — | — | WO | disclosed |