Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633476 | 1.00 | LTA4H (0.41) | LTA4HL3MBTL1TDP1ALDH1A1TP53 | |
| SCHEMBL17760955 | 1.00 | LTA4H (0.41) | LTA4HL3MBTL1TDP1ALDH1A1TP53 | |
| SCHEMBL19726543 | 0.91 | ALDH1A1 (0.38) | LTA4HL3MBTL1TDP1ALDH1A1TP53 | |
| SCHEMBL17901214 | 0.91 | ALDH1A1 (0.38) | LTA4HL3MBTL1TDP1ALDH1A1TP53 | |
| SCHEMBL19714472 | 0.91 | ALDH1A1 (0.38) | LTA4HL3MBTL1TDP1ALDH1A1TP53 | |
| SCHEMBL19633669 | 0.88 | LTA4H (0.41) | LTA4HL3MBTL1TDP1ALDH1A1AOC3 | |
| SCHEMBL19614764 | 0.88 | LTA4H (0.41) | LTA4HL3MBTL1TDP1ALDH1A1AOC3 | |
| SCHEMBL19614767 | 0.88 | LTA4H (0.41) | LTA4HL3MBTL1TDP1ALDH1A1AOC3 | |
| SCHEMBL14368630 | 0.85 | LTA4H (0.45) | LTA4HL3MBTL1TDP1ALDH1A1TP53 | |
| SCHEMBL13041180 | 0.85 | LTA4H (0.45) | LTA4HL3MBTL1TDP1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | LTA4H 2653/4885L3MBTL1 3973/4885TDP1 2703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.