SCHEMBL19615784

SCHEMBL19615784

N=C(N)NC(CP(=O)(O)O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.43
ANPEP P15144 2/20 0.41
ACP3 P15309 8/20 0.41
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
KMT2A Q03164 1/20 0.40
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
LAP3 P28838 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19614990 0.81 PLAU (0.41) SRCANPEPMEN1KMT2ALAP3
SCHEMBL14335168 0.79 KDM4E (0.55) MEN1KMT2A
SCHEMBL14335289 0.79 KMT2A (0.48) SRCACP3MEN1CYP1A2KMT2A
SCHEMBL14368141 0.78 RIPK1 (0.49)
SCHEMBL11400562 0.77 ITGB3 (0.58) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL5400591 0.76 RIPK1 (0.47)
SCHEMBL7521194 0.76 ITGB3 (0.38) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL5400597 0.76 RIPK1 (0.47)
SCHEMBL28039671 0.75 CA9 (0.56) SRCACP3MEN1CYP1A2KMT2A
SCHEMBL27287608 0.74 ITGB3 (0.46) CYP1A2ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458072-B1 BIS(ACETAMIDOPHENYL) GUANIDINOPHENYLETHYLPHOSPHONATES FOR USE IN THE PREVENTION AND/OR TREATMENT OF PAR-RELATED DISEASES UNIV ANTWERPEN (BE) 2020-09-30 EP disclosed
EP-3458072-A1 BIS(ACETAMIDOPHENYL) GUANIDINOPHENYLETHYLPHOSPHONATES FOR USE IN THE PREVENTION AND/OR TREATMENT OF PAR-RELATED DISEASES Universiteit Antwerpen (BE) 2019-03-27 EP disclosed
WO-2017198753-A1 BIS(ACETAMIDOPHENYL) GUANIDINOPHENYLETHYLPHOSPHONATES FOR USE IN THE PREVENTION AND/OR TREATMENT OF PAR-RELATED DISEASES UNIVERSITEIT ANTWERPEN (BE) 2017-11-23 WO disclosed
US-20150349269-A1 LUMINESCENT MATERIAL FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE CHEIL INDUSTRIES INC. (KR) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150349269-A1 LUMINESCENT MATERIAL FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OCIAD1, OR10J3, OCIAD2 SRC 2567/4885ANPEP 3650/4885ACP3 4671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.