Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | MMP14 | P50281 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | ACP3 | P15309 | 7/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514574 | 0.77 | SRC (0.46) | SRCACP3MEN1KMT2ACYP1A2 | |
| SCHEMBL14335289 | 0.76 | KMT2A (0.48) | SRCACP3LMNAMEN1KMT2A | |
| SCHEMBL14335168 | 0.76 | KDM4E (0.55) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL11450263 | 0.76 | CA9 (0.62) | CA9CA12SRCMMP8MMP14 | |
| SCHEMBL8623190 | 0.76 | CA9 (0.45) | CA9CA12SRCMMP8MMP14 | |
| SCHEMBL20095129 | 0.75 | MAPKAPK2 (0.54) | NPSR1LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL430689 | 0.75 | MAPKAPK2 (0.54) | NPSR1LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL27783713 | 0.75 | MAPKAPK2 (0.54) | NPSR1LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL19615784 | 0.75 | SRC (0.43) | SRCACP3MEN1KMT2ACYP1A2 | |
| SCHEMBL875769 | 0.74 | SRC (0.60) | SRCACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106892942-B | A kind of preparation method of beta-amido ethylphosphonic acid derivative | 苏州大学 | 2019-01-04 | — | — | CN | disclosed |
| CN-106892942-A | A kind of preparation method of β amidos ethylphosphonic acid derivative | 苏州大学 | 2017-06-27 | — | — | CN | disclosed |
| CN-105017312-B | Preparation method of beta-aminoethyl phosphono derivative | 苏州大学 | 2017-05-10 | — | — | CN | disclosed |
| CN-105017312-A | Preparation method of beta-aminoethyl phosphono derivative | UNIV SOOCHOW | 2015-11-04 | — | — | CN | disclosed |