Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 3/20 | 0.50 |
| ▸ | TKT | P29401 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456311 | 0.84 | TRPV4 (0.57) | TRPV4DAOTKTKDM1AMAOA | |
| SCHEMBL991369 | 0.81 | DAO (0.50) | TRPV4DAOTKTKDM1AMAOA | |
| SCHEMBL694114 | 0.81 | DAO (0.50) | TRPV4DAOTKTKDM1AMAOA | |
| SCHEMBL1259004 | 0.81 | TKT (0.55) | TRPV4DAOTKTKDM1AMAOA | |
| SCHEMBL3851699 | 0.81 | DAO (0.50) | TRPV4DAOTKTKDM1AMAOA | |
| SCHEMBL264730 | 0.81 | TAAR1 (0.52) | TRPV4DAOTKTKDM1AMAOA | |
| SCHEMBL12224352 | 0.78 | NFKB1 (0.50) | TRPV4DAOTKTKDM1AMAOA | |
| SCHEMBL31067892 | 0.78 | TKT (0.49) | TRPV4DAOTKTKDM1AMAOA | |
| SCHEMBL14028936 | 0.78 | TKT (0.49) | TRPV4DAOTKTKDM1AMAOA | |
| SCHEMBL991269 | 0.78 | DAO (0.48) | TRPV4DAOTKTKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2017198812-A2 | PROCESS FOR THE MANUFACTURE OF 2-SUBSTITUTED-5-(1-METHYLTHIO)ALKYLPYRIDINES | SOLVAY SA (BE) | 2017-11-23 | — | — | WO | disclosed |