Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856059 | 0.85 | MAPT (0.59) | MAPTKDM4EMAPK1HSD17B10LMNA | |
| SCHEMBL11062650 | 0.85 | KDM4E (0.47) | MAPTKDM4EMAPK1HSD17B10LMNA | |
| SCHEMBL31335961 | 0.83 | MAPT (0.62) | MAPTKDM4EMAPK1HSD17B10LMNA | |
| SCHEMBL57368 | 0.83 | MAPT (0.62) | MAPTKDM4EMAPK1HSD17B10LMNA | |
| SCHEMBL28855172 | 0.83 | CA12 (0.41) | MAPTKDM4EHSD17B10LMNATDP1 | |
| SCHEMBL24136599 | 0.81 | LMNA (0.55) | MAPTKDM4EMAPK1HSD17B10LMNA | |
| SCHEMBL30466421 | 0.81 | LMNA (0.55) | MAPTKDM4EMAPK1HSD17B10LMNA | |
| SCHEMBL3761829 | 0.81 | CA12 (0.53) | MAPTKDM4EHSD17B10LMNATDP1 | |
| SCHEMBL30466430 | 0.81 | CA12 (0.53) | MAPTKDM4EHSD17B10LMNATDP1 | |
| SCHEMBL22219653 | 0.80 | GAA (0.50) | MAPTKDM4EMAPK1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017199227-A1 | PROCESS FOR PREPARATION OF 3,4-DIHYDROXY-2-METHYL BENZOIC ACID ALKYLESTER | S & I OPHTHALMIC, LLC. (US) | 2017-11-23 | — | — | WO | disclosed |
| WO-2017199227-A1 | PROCESS FOR PREPARATION OF 3,4-DIHYDROXY-2-METHYL BENZOIC ACID ALKYLESTER | S & I OPHTHALMIC, LLC. (US) | 2017-11-23 | — | — | WO | disclosed |