Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136599 | 1.00 | LMNA (0.55) | LMNASMN1; SMN2MAPK1MAPTTDP1 | |
| SCHEMBL11062650 | 0.89 | KDM4E (0.47) | LMNASMN1; SMN2MAPK1MAPTTDP1 | |
| SCHEMBL16513023 | 0.85 | HTT (0.50) | LMNASMN1; SMN2MAPK1MAPTTDP1 | |
| Methyl 2,3,4-Trimethoxybenzoate SCHEMBL1434191 | 0.85 | ALDH1A1 (0.57) | MAPTTDP1KDM4EPOLBALDH1A1 | |
| SCHEMBL7437362 | 0.84 | LMNA (0.55) | LMNASMN1; SMN2MAPK1MAPTTDP1 | |
| SCHEMBL10459350 | 0.83 | CHEK1 (0.53) | LMNASMN1; SMN2MAPK1MAPTTDP1 | |
| SCHEMBL2425023 | 0.83 | MAPT (0.68) | LMNASMN1; SMN2MAPK1MAPTTDP1 | |
| SCHEMBL10740410 | 0.83 | LMNA (0.56) | LMNASMN1; SMN2MAPK1MAPTTDP1 | |
| SCHEMBL30466426 | 0.83 | MAPT (0.68) | LMNASMN1; SMN2MAPK1MAPTTDP1 | |
| SCHEMBL13117414 | 0.82 | GAA (0.48) | LMNASMN1; SMN2MAPK1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194108-B | Novel dioxoisoquinolinone derivatives and use thereof | 韩美药品株式会社 | 2025-05-30 | — | — | CN | disclosed |
| CN-113423710-B | Novel heterocyclic tricyclic derivative compounds and use thereof | 韩美药品株式会社 | 2024-06-14 | — | — | CN | disclosed |
| CN-116194108-A | Novel dioxoisoquinolinone derivatives and use thereof | 韩美药品株式会社 | 2023-05-30 | — | — | CN | disclosed |