SCHEMBL19615909

SCHEMBL19615909

CC(C)CC(NC(=O)OCc1ccccc1)C(O)CC(=O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
REN P00797 6/20 0.56
CTSK P43235 8/20 0.55
CTSL P07711 4/20 0.52
CTSB P07858 4/20 0.52
CTSS P25774 2/20 0.52
PSMB1 P20618 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19615907 1.00 REN (0.56) RENCTSKCTSLCTSBCTSS
SCHEMBL7293600 0.90 REN (0.58) RENCTSKCTSLCTSBCTSS
SCHEMBL10420156 0.90 REN (0.58) RENCTSKCTSLCTSBCTSS
SCHEMBL19615642 0.88 TRPM8 (0.49) CTSKCTSLCTSBCTSS
SCHEMBL19615638 0.88 TRPM8 (0.49) CTSKCTSLCTSBCTSS
SCHEMBL3042936 0.85 CTSK (0.57) RENCTSKCTSLCTSBCTSS
SCHEMBL6502695 0.85 CTSK (0.57) RENCTSKCTSLCTSBCTSS
SCHEMBL3042938 0.85 CTSK (0.57) RENCTSKCTSLCTSBCTSS
SCHEMBL29865843 0.85 CTSK (0.57) RENCTSKCTSLCTSBCTSS
SCHEMBL19615498 0.85 ATM (0.52) CTSKCTSLCTSBCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458584-B1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN CONSEJO SUPERIOR INVESTIGACION (ES) 2021-07-07 EP disclosed
US-10683493-B2 Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2020-06-16 US disclosed
US-20190194638-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN TECHNICAL UNIVERSITY OF DARMSTADT (DE) 2019-06-27 US disclosed
EP-3458584-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN Consejo Superior De Investigaciones Científicas (ES) 2019-03-27 EP disclosed
WO-2017198717-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2017-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194638-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN ALDOA, TALDO1, DERA REN 375/4885CTSK 2864/4885CTSL 3343/4885
US-10683493-B2 Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein ALDOA, TALDO1, DERA REN 375/4885CTSK 2864/4885CTSL 3343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.