SCHEMBL19616499

SCHEMBL19616499

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O[C@@H](CO)C(OP(=O)(O)OCCN)C(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.53
GPR55 Q9Y2T6 2/20 0.49
SELP P16109 1/20 0.49
ALDH1A1 P00352 2/20 0.49
MAPT P10636 2/20 0.49
CNR1 P21554 2/20 0.49
THRB P10828 1/20 0.49
FAAH O00519 1/20 0.49
HPGD P15428 1/20 0.49
CNR2 P34972 1/20 0.49
NR5A2 O00482 1/20 0.45
NR5A1 Q13285 1/20 0.45
DAGLA Q9Y4D2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9951800 1.00 S1PR1 (0.53) S1PR1GPR55SELPALDH1A1MAPT
SCHEMBL9951272 0.99 S1PR1 (0.54) S1PR1GPR55SELPALDH1A1MAPT
SCHEMBL479264 0.99 S1PR1 (0.54) S1PR1GPR55SELPALDH1A1MAPT
SCHEMBL8632106 0.96 S1PR1 (0.52) S1PR1GPR55SELPALDH1A1MAPT
SCHEMBL9951988 0.96 S1PR1 (0.49) S1PR1SELPDAGLA
SCHEMBL2340054 0.96 S1PR1 (0.49) S1PR1SELPDAGLA
SCHEMBL17595343 0.96 S1PR1 (0.49) S1PR1SELPDAGLA
SCHEMBL8627715 0.90 S1PR1 (0.46) S1PR1GPR55SELPALDH1A1MAPT
SCHEMBL16964730 0.88 P2RY10 (0.43) S1PR1
SCHEMBL9166758 0.88 PLA2G2C (0.43) MAPTDAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458083-A1 POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF Modernatx, Inc. (US) 2019-03-27 EP claimed
EP-3458092-A1 MRNA COMBINATION THERAPY FOR THE TREATMENT OF CANCER Modernatx, Inc. (US) 2019-03-27 EP claimed
WO-2017201352-A1 MRNA COMBINATION THERAPY FOR THE TREATMENT OF CANCER MODERNATX, INC. (US) 2017-11-23 WO claimed
WO-2017201350-A1 POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF MODERNATX, INC. (US) 2017-11-23 WO claimed
WO-2026090590-A1 NANOPARTICLE FORMULATIONS FOR THE DELIVERY OF DNA TO ADIPOSE TISSUE Remedium Bio, Inc. (US) 2026-04-30 WO disclosed
WO-2023212618-A1 LIPID NANOPARTICLES COMPRISING VENEZUELAN EQUINE ENCEPHALITIS (VEE) REPLICON AND USES THEREOF STRAND THERAPEUTICS INC. (US) 2023-11-02 WO disclosed
EP-3458092-A1 MRNA COMBINATION THERAPY FOR THE TREATMENT OF CANCER Modernatx, Inc. (US) 2019-03-27 EP disclosed
EP-3458474-A1 COMBINATIONS OF MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF Modernatx, Inc. (US) 2019-03-27 EP disclosed
WO-2017201352-A1 MRNA COMBINATION THERAPY FOR THE TREATMENT OF CANCER MODERNATX, INC. (US) 2017-11-23 WO disclosed
WO-2017201325-A1 COMBINATIONS OF MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF MODERNATX, INC. (US) 2017-11-23 WO disclosed