Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.41 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628861 | 0.97 | P2RY10 (0.43) | S1PR1P2RY10GPR34 | |
| SCHEMBL9951880 | 0.91 | PLA2G2C (0.45) | P2RY10GPR34 | |
| SCHEMBL4737508 | 0.91 | PLA2G2C (0.45) | P2RY10GPR34 | |
| SCHEMBL9951445 | 0.91 | PLA2G2C (0.45) | P2RY10GPR34 | |
| SCHEMBL479264 | 0.91 | S1PR1 (0.54) | S1PR1ALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL9951272 | 0.91 | S1PR1 (0.54) | S1PR1ALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL19616499 | 0.90 | S1PR1 (0.53) | S1PR1ALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL9951800 | 0.90 | S1PR1 (0.53) | S1PR1ALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL16964730 | 0.88 | P2RY10 (0.43) | S1PR1P2RY10GPR34 | |
| SCHEMBL8632106 | 0.88 | S1PR1 (0.52) | S1PR1ALDH1A1MAPTTHRBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0845981-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES | GENZYME CORPORATION (US) | 1998-06-10 | — | — | EP | claimed |
| WO-1997046223-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES | GENZYME CORPORATION (US) | 1997-12-11 | — | — | WO | claimed |
| WO-2012143514-A1 | METHOD FOR THE DIAGNOSIS OF LIVER INJURY BASED ON A METABOLOMIC PROFILE | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2012-10-26 | — | — | WO | disclosed |