Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.43 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951988 | 0.91 | S1PR1 (0.49) | LPAR1DAGLAP2RY10GPR34 | |
| SCHEMBL2340054 | 0.91 | S1PR1 (0.49) | LPAR1DAGLAP2RY10GPR34 | |
| SCHEMBL17595343 | 0.91 | S1PR1 (0.49) | LPAR1DAGLAP2RY10GPR34 | |
| SCHEMBL18554683 | 0.89 | PLA2G2C (0.40) | PLA2G2CLPAR3LPAR1LPAR6LPAR4 | |
| SCHEMBL9951272 | 0.88 | S1PR1 (0.54) | MAPTDAGLAP2RY10GPR34 | |
| SCHEMBL479264 | 0.88 | S1PR1 (0.54) | MAPTDAGLAP2RY10GPR34 | |
| SCHEMBL9951800 | 0.88 | S1PR1 (0.53) | MAPTDAGLA | |
| SCHEMBL19616499 | 0.88 | S1PR1 (0.53) | MAPTDAGLA | |
| SCHEMBL8632106 | 0.86 | S1PR1 (0.52) | MAPTDAGLAP2RY10 | |
| SCHEMBL4737508 | 0.86 | PLA2G2C (0.45) | PLA2G2CP2RY10GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636134-A1 | NOVEL ACYLATED PHOSPHOLIPID DRUGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-02-01 | — | — | EP | disclosed |