Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | SELP | P16109 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951272 | 0.97 | S1PR1 (0.54) | S1PR1SELPGPR55ALDH1A1MAPT | |
| SCHEMBL479264 | 0.97 | S1PR1 (0.54) | S1PR1SELPGPR55ALDH1A1MAPT | |
| SCHEMBL9951800 | 0.96 | S1PR1 (0.53) | S1PR1SELPGPR55ALDH1A1MAPT | |
| SCHEMBL19616499 | 0.96 | S1PR1 (0.53) | S1PR1SELPGPR55ALDH1A1MAPT | |
| SCHEMBL9951988 | 0.95 | S1PR1 (0.49) | S1PR1SELPDAGLAP2RY10 | |
| SCHEMBL17595343 | 0.95 | S1PR1 (0.49) | S1PR1SELPDAGLAP2RY10 | |
| SCHEMBL2340054 | 0.95 | S1PR1 (0.49) | S1PR1SELPDAGLAP2RY10 | |
| SCHEMBL8627715 | 0.88 | S1PR1 (0.46) | S1PR1SELPGPR55ALDH1A1MAPT | |
| SCHEMBL16964730 | 0.86 | P2RY10 (0.43) | S1PR1P2RY10 | |
| SCHEMBL9166758 | 0.86 | PLA2G2C (0.43) | MAPTDAGLAP2RY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0845981-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES | GENZYME CORPORATION (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997046223-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES | GENZYME CORPORATION (US) | 1997-12-11 | — | — | WO | disclosed |