Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30747187 | 0.76 | ARG1 (0.33) | ARG1ARG2 | |
| SCHEMBL4711308 | 0.62 | ARG1 (0.36) | ARG1ARG2 | |
| SCHEMBL7589446 | 0.62 | KDM4E (0.31) | — | |
| SCHEMBL28414784 | 0.61 | — | — | |
| SCHEMBL30747078 | 0.60 | — | — | |
| SCHEMBL31603619 | 0.59 | — | — | |
| SCHEMBL16967366 | 0.58 | ARG1 (0.49) | ARG1ARG2 | |
| SCHEMBL29618982 | 0.58 | — | — | |
| SCHEMBL14839486 | 0.58 | — | — | |
| Succinic Acid SCHEMBL21436621 | 0.58 | EGLN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458445-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017201161-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2017-11-23 | — | — | WO | disclosed |