Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297712 | 0.86 | ALDH1A1 (0.47) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL17174586 | 0.84 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL30688593 | 0.76 | LMNA (0.51) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL9308235 | 0.76 | TK1 (0.52) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL9311032 | 0.75 | TK1 (0.60) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL19619045 | 0.74 | TK1 (0.51) | TK1 | |
| SCHEMBL15743265 | 0.74 | TOP2A (0.42) | TK1 | |
| SCHEMBL19619013 | 0.74 | TOP2A (0.42) | TK1 | |
| SCHEMBL9470674 | 0.74 | LMNA (0.55) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL10171803 | 0.74 | LMNA (0.55) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822137-B2 | Phosphonucleosides useful in the treatment of viral disorders | UNIVERSITY COLLEGE CORK (IE) | 2017-11-21 | — | — | US | disclosed |