Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | IL18 | Q14116 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12956396 | 0.83 | CNR1 (0.51) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL29316168 | 0.82 | MMP3 (0.48) | GAAKMT2AMAPTMEN1PAX8 | |
| SCHEMBL11886544 | 0.81 | LMNA (0.44) | GAAKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL29322120 | 0.80 | MMP3 (0.47) | GAAKMT2APAX8TDP1ATM | |
| SCHEMBL29316174 | 0.79 | MMP3 (0.52) | GAAKMT2APAX8TDP1ATM | |
| SCHEMBL29316177 | 0.78 | HDAC1 (0.53) | GAAKMT2APAX8TDP1POLB | |
| SCHEMBL29322132 | 0.78 | HDAC1 (0.53) | GAAKMT2APAX8TDP1POLB | |
| SCHEMBL9908140 | 0.77 | MAPT (0.41) | GAAKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL5329961 | 0.74 | SCN8A (0.42) | MAPTALDH1A1KDM4ETDP1POLB | |
| SCHEMBL29316162 | 0.72 | TRPA1 (0.52) | KMT2AMAPTALDH1A1MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822206-B2 | Copolymers for near-infrared radiation-sensitive coating compositions for positive-working thermal lithographic printing plates | MYLAN GROUP (VN) | 2017-11-21 | — | — | US | disclosed |