SCHEMBL19619138

SCHEMBL19619138

CN1CCC(NOC(C)(C)C)CC1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 12/20 0.35
POLB P06746 1/20 0.35
NCF1 P14598 1/20 0.32
SSTR1 P30872 5/20 0.32
KDM1A O60341 1/20 0.32
DPP7 Q9UHL4 1/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15382436 0.81
SCHEMBL3656575 0.77 BTK (0.35) EPHX1
SCHEMBL12061481 0.75 POLB (0.38) SSTR4POLBNCF1SSTR1KDM1A
SCHEMBL27550499 0.75 ALDH1A1 (0.39) EPHX1
SCHEMBL17527844 0.71 EPHX1 (0.37) SSTR4POLBSSTR1KDM1AEPHX1
SCHEMBL27540896 0.71 KDM1A (0.33) KDM1A
SCHEMBL13413240 0.71 SSTR4 (0.39) SSTR4SSTR1
SCHEMBL4569280 0.70 POLB (0.38) SSTR4POLBNCF1SSTR1KDM1A
SCHEMBL12853144 0.70 NCF1 (0.37) SSTR4POLBNCF1SSTR1KDM1A
SCHEMBL4589796 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9820488-B2 Compounds for the control of endoparasites ELANCO TIERGESUNDHEIT AG (CH) 2017-11-21 US disclosed