Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22832244 | 1.00 | MIF (0.42) | MIFTSHRPDCD1CD274PLA2G7 | |
| SCHEMBL8259717 | 0.85 | MIF (0.52) | MIFPLA2G7MEN1KMT2ACA1 | |
| SCHEMBL8126152 | 0.85 | MIF (0.52) | MIFPLA2G7MEN1KMT2ACA1 | |
| SCHEMBL13201409 | 0.85 | MIF (0.52) | MIFPLA2G7MEN1KMT2ACA1 | |
| SCHEMBL8125280 | 0.85 | MIF (0.52) | MIFPLA2G7MEN1KMT2ACA1 | |
| SCHEMBL1962034 | 0.85 | MIF (0.52) | MIFPLA2G7MEN1KMT2ACA1 | |
| SCHEMBL1962036 | 0.85 | MIF (0.52) | MIFPLA2G7MEN1KMT2ACA1 | |
| SCHEMBL1830261 | 0.82 | MEN1 (0.50) | MIFTSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9778970 | 0.82 | MEN1 (0.50) | MIFTSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1959830 | 0.82 | MEN1 (0.50) | MIFTSHRMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590089-B2 | Processes for preparing toll-like receptor modulator compounds | GILEAD SCIENCES, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| US-20220274985-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | GILEAD SCIENCES, INC. | 2022-09-01 | — | — | US | disclosed |
| EP-3990455-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-05-04 | — | — | EP | disclosed |
| US-11286257-B2 | Processes for preparing toll-like receptor modulator compounds | GILEAD SCIENCES, INC. (US) | 2022-03-29 | — | — | US | disclosed |
| US-20210017170-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | GILEAD SCIENCES, INC. | 2021-01-21 | — | — | US | disclosed |
| WO-2020264081-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| US-20090221640-A1 | Novel Crystal Modifications | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | disclosed |
| US-20090221640-A1 | Novel Crystal Modifications | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12590089-B2 | Processes for preparing toll-like receptor modulator compounds | TLR8, MYD88, TLR6 | MIF 20/4885TSHR 946/4885PDCD1 1126/4885 |
| US-20220274985-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | TLR4, TLR3, TLR6 | MIF 232/4885TSHR 447/4885PDCD1 1668/4885 |
| US-20210017170-A1 | PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS | TLR4, TLR3, TLR6 | MIF 232/4885TSHR 447/4885PDCD1 1668/4885 |
| US-11286257-B2 | Processes for preparing toll-like receptor modulator compounds | TLR4, TLR3, TLR6 | MIF 232/4885TSHR 447/4885PDCD1 1668/4885 |
| US-20090221640-A1 | Novel Crystal Modifications | PTMS, NT5C, CDK5 | MIF 4247/4885TSHR 1278/4885PDCD1 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.