Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | WRN | Q14191 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1652027 | 0.83 | THRB (0.64) | THRBNAAATSHRDGKAGAA | |
| SCHEMBL5408195 | 0.81 | TSHR (0.48) | THRBTSHRGAARAD52NPSR1 | |
| SCHEMBL15078188 | 0.81 | THRB (0.61) | THRBTSHRALDH1A1HTTMAPT | |
| SCHEMBL6898581 | 0.81 | ALDH1A1 (0.46) | THRBTSHRGAAALDH1A1HTT | |
| SCHEMBL5408269 | 0.80 | THRB (0.71) | THRBTSHRALDH1A1MAPTHIF1A | |
| SCHEMBL14934926 | 0.79 | THRB (0.44) | THRBTSHRALDH1A1KDM4EMAPT | |
| SCHEMBL18214984 | 0.78 | THRB (0.69) | THRBNAAATSHRDGKAGAA | |
| Ethylene SCHEMBL6759867 | 0.78 | NAAA (0.58) | THRBNAAATSHRDGKAGAA | |
| Ethylene SCHEMBL9937082 | 0.78 | NAAA (0.58) | THRBNAAATSHRDGKAGAA | |
| SCHEMBL5411942 | 0.78 | TSHR (0.60) | THRBNAAATSHRRAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768872-B1 | METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS | SIRRUS INC (US) | 2017-11-22 | — | — | EP | disclosed |