Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | HTR2B | P41595 | 4/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10019611 | 0.90 | RIPK1 (0.34) | RIPK1PDK2HTR2CHTR2BBRD4 | |
| SCHEMBL10020060 | 0.87 | ALOX5AP (0.36) | RIPK1HTR2CHTR2BHTR2A | |
| SCHEMBL10019616 | 0.82 | RIPK1 (0.32) | RIPK1HTR2CHTR2BHTR2A | |
| SCHEMBL10019811 | 0.81 | PDK2 (0.41) | PDK2 | |
| SCHEMBL9561997 | 0.80 | RIPK1 (0.46) | KCNN4RIPK1HTR2CHTR2BHTR7 | |
| SCHEMBL9561995 | 0.80 | RIPK1 (0.46) | KCNN4RIPK1HTR2CHTR2BHTR7 | |
| SCHEMBL19622158 | 0.80 | MAOA (0.33) | HTR2CHTR2A | |
| SCHEMBL10019885 | 0.79 | CYP2C9 (0.32) | — | |
| SCHEMBL10019810 | 0.79 | PDK2 (0.43) | PDK2 | |
| SCHEMBL10019969 | 0.79 | L3MBTL1 (0.41) | KCNN4PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2669263-B1 | COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2017-11-22 | — | — | EP | disclosed |