Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TEK | Q02763 | 2/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16206235 | 0.84 | CYP19A1 (0.70) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL3777940 | 0.81 | CYP19A1 (0.66) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL13977955 | 0.81 | CYP19A1 (0.71) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL15108602 | 0.81 | CYP19A1 (0.66) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL935182 | 0.79 | CYP19A1 (1.00) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| Bromide SCHEMBL1887515 | 0.79 | CYP19A1 (0.64) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL2686847 | 0.78 | CYP19A1 (0.62) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL15589760 | 0.78 | CYP19A1 (0.62) | CYP19A1NPC1RAB9APTGS2HDAC8 | |
| SCHEMBL12022152 | 0.78 | CYP19A1 (0.62) | CYP19A1NPC1RAB9AEPHB4MEN1 | |
| SCHEMBL16264704 | 0.78 | CYP19A1 (0.62) | CYP19A1NPC1RAB9ATEKEPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870141-B1 | METHANETHIONE COMPOUNDS HAVING ANTIVIRAL ACTIVITY | VIRONOVA INFLUENZA AB (SE) | 2017-11-22 | — | — | EP | disclosed |