Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 3/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.51 |
| ▸ | TEK | Q02763 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1887515 | 0.98 | CYP19A1 (0.64) | CYP19A1NPC1RAB9AKDREPHB4 | |
| SCHEMBL16264704 | 0.96 | CYP19A1 (0.62) | CYP19A1NPC1RAB9AKDREPHB4 | |
| SCHEMBL16264735 | 0.85 | MEN1 (0.50) | CYP19A1NPC1RAB9AKDREPHB4 | |
| SCHEMBL12022152 | 0.85 | CYP19A1 (0.62) | CYP19A1NPC1RAB9AKDREPHB4 | |
| SCHEMBL16206235 | 0.84 | CYP19A1 (0.70) | CYP19A1NPC1RAB9AKDREPHB4 | |
| Bromide SCHEMBL1883296 | 0.84 | CYP19A1 (0.60) | CYP19A1NPC1RAB9AKDREPHB4 | |
| SCHEMBL9137418 | 0.83 | SRC (0.60) | CYP19A1NPC1RAB9AKDREPHB4 | |
| SCHEMBL12022150 | 0.82 | CYP19A1 (0.58) | CYP19A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL17697510 | 0.82 | CYP19A1 (0.58) | CYP19A1NPC1RAB9AKDREPHB4 | |
| SCHEMBL3407901 | 0.82 | CYP19A1 (0.47) | CYP19A1NPC1RAB9AKDREPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364277-A1 | E-SELECTIN TARGETING AGENTS | GLYCOMIMETICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230255950-A1 | 3-(Hydroxy)-Pyridin-4(1H)-One Compounds and Methods of Making and Using the Same | GEORGIA TECH RESEARCH CORPORATION | 2023-08-17 | — | — | US | disclosed |
| US-11654137-B2 | 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same | GEORGIA TECH RESEARCH CORPORATION (US) | 2023-05-23 | — | — | US | disclosed |
| US-11242331-B2 | Analogs of yohimbine and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-02-08 | — | — | US | disclosed |
| US-20210000811-A1 | 3-(HYDROXY)-PYRIDIN-4(1H)-ONE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GEORGIA TECH RESEARCH CORPORATION (US) | 2021-01-07 | — | — | US | disclosed |
| US-20190256490-A1 | ANALOGS OF YOHIMBINE AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-08-22 | — | — | US | disclosed |
| WO-2018095344-A1 | ISOCITRATE DEHYDROGENASE (IDH) INHIBITOR | SHANGHAI METON PHARMACEUTICAL CO., LTD (CN) | 2018-05-31 | — | — | WO | disclosed |
| EP-2999707-B1 | TYLOSIN DERIVATIVES AND METHOD FOR PREPARATION THEREOF | BAYER ANIMAL HEALTH GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| WO-2017218702-A1 | PHOSPHOLIPID ETHER ANALOGS FOR THE IDENTIFICATION AND ISOLATION OF CIRCULATING TUMOR CELLS | CELLECTAR BIOSCIENCES, INC. (US) | 2017-12-21 | — | — | WO | disclosed |
| EP-2782922-B1 | ANTIBACTERIAL TYLOSIN DERIVATIVES AND METHODS FOR THEIR PREPARATION | BAYER IP GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-20130274212-A1 | Sesterterpene Compounds and Use Thereof | SNU R&DB FOUNDATION (KR) | 2013-10-17 | — | — | US | disclosed |
| US-20120309794-A1 | COMPOUNDS INHIBITORS OF ENZYME LACTATE DEHYDROGENASE (LDH) AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | UNIVERSITÀ DI PISA (IT) | 2012-12-06 | — | — | US | disclosed |
| US-8197903-B2 | Surface modified organic inorganic hybrid glass, protecting group induced alcohol or its derivative and producing method thereof | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2012-06-12 | — | — | US | disclosed |
| US-20110294972-A1 | Olefin Polymerization Catalysts | BASELL POLYOLEFINE GMBH (DE) | 2011-12-01 | — | — | US | disclosed |
| US-20110294972-A1 | Olefin Polymerization Catalysts | BASELL POLYOLEFINE GMBH (DE) | 2011-12-01 | — | — | US | disclosed |
| EP-2201006-A1 | (R)-4-(HETEROARYL) PHENYLETHYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompé S.p.a. (IT) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009050258-A1 | (R)-4-(HETEROARYL) PHENYLETHYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompé S.p.A. (IT) | 2009-04-23 | — | — | WO | disclosed |
| US-20090004140-A1 | 4-SUBSTITUTED PYRROLIDINE AS ANTI-INFECTIVES | ENANTA PHARMACEUTICALS, INC. | 2009-01-01 | — | — | US | disclosed |
| US-20090004140-A1 | 4-SUBSTITUTED PYRROLIDINE AS ANTI-INFECTIVES | ENANTA PHARMACEUTICALS, INC. | 2009-01-01 | — | — | US | disclosed |
| WO-2009003009-A1 | SUBSTITUTED PYRROLIDINE AS ANTI-INFECTIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11654137-B2 | 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same | KDM1B, KDM3A, KDM1A | CYP19A1 2689/4885NPC1 4132/4885RAB9A 3914/4885 |
| US-20230255950-A1 | 3-(Hydroxy)-Pyridin-4(1H)-One Compounds and Methods of Making and Using the Same | KDM1B, KDM3A, KDM1A | CYP19A1 2689/4885NPC1 4132/4885RAB9A 3914/4885 |
| US-20210000811-A1 | 3-(HYDROXY)-PYRIDIN-4(1H)-ONE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | KDM1B, KDM3A, KDM1A | CYP19A1 2689/4885NPC1 4132/4885RAB9A 3914/4885 |
| US-20090004140-A1 | 4-SUBSTITUTED PYRROLIDINE AS ANTI-INFECTIVES | EIF2AK2, RNGTT, POLR2E | CYP19A1 2054/4885NPC1 185/4885RAB9A 2536/4885 |
| US-11242331-B2 | Analogs of yohimbine and uses thereof | MAOA, MAOB, NPY5R | CYP19A1 218/4885NPC1 4254/4885RAB9A 1606/4885 |
| US-20110294972-A1 | Olefin Polymerization Catalysts | AOC3, PCNA, ORC3 | CYP19A1 1716/4885NPC1 3358/4885RAB9A 4807/4885 |
| US-20120309794-A1 | COMPOUNDS INHIBITORS OF ENZYME LACTATE DEHYDROGENASE (LDH) AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | LDHA, LDHB, DLD | CYP19A1 1141/4885NPC1 1519/4885RAB9A 2969/4885 |
| US-20130274212-A1 | Sesterterpene Compounds and Use Thereof | LIPC, LIPE, FABP4 | CYP19A1 814/4885NPC1 458/4885RAB9A 2494/4885 |
| US-20230364277-A1 | E-SELECTIN TARGETING AGENTS | SELE, SELPLG, SELP | CYP19A1 4768/4885NPC1 1147/4885RAB9A 1624/4885 |
| US-20190256490-A1 | ANALOGS OF YOHIMBINE AND USES THEREOF | MAOA, MAOB, NPY5R | CYP19A1 218/4885NPC1 4254/4885RAB9A 1606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.