Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TEK | Q02763 | 2/20 | 0.55 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16206235 | 0.84 | CYP19A1 (0.70) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL935182 | 0.83 | CYP19A1 (1.00) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL15589760 | 0.81 | CYP19A1 (0.62) | CYP19A1NPC1RAB9APTGS2HDAC8 | |
| SCHEMBL15108602 | 0.81 | CYP19A1 (0.66) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL3777940 | 0.81 | CYP19A1 (0.66) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL19622150 | 0.81 | CYP19A1 (0.66) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL18625821 | 0.80 | CYP19A1 (0.60) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL16206204 | 0.80 | CYP19A1 (0.79) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| SCHEMBL15836586 | 0.79 | CYP19A1 (0.93) | CYP19A1NPC1RAB9ATEKEPHB4 | |
| Bromide SCHEMBL1887515 | 0.79 | CYP19A1 (0.64) | CYP19A1NPC1RAB9ATEKEPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160263258-A1 | Radiotracer introduced [18F]fluoromethyl group targeting neuroinflammation for PET imaging and Synthesis of Radiotracer and its biological evaluation Method for Radiotracer | BIO IMAGING KOREA CO., LTD. | 2016-09-15 | — | — | US | claimed |
| CN-105530961-A | [18f]fluoromethyl group-introduced radiotracer for positron emission tomography for targeting brain neuroinflammation, synthesis thereof, and method for evaluating biological results using same | BIO IMAGING KOREA CO LTD | 2016-04-27 | — | — | CN | claimed |
| US-9505799-B2 | 18F-labeled precursor of PET radioactive medical supplies, and preparation method thereof | FUTURECHEM CO., LTD. (KR) | 2016-11-29 | — | — | US | disclosed |
| US-9505799-B2 | 18F-labeled precursor of PET radioactive medical supplies, and preparation method thereof | FUTURECHEM CO., LTD. (KR) | 2016-11-29 | — | — | US | disclosed |
| US-9505799-B2 | 18F-labeled precursor of PET radioactive medical supplies, and preparation method thereof | FUTURECHEM CO., LTD. (KR) | 2016-11-29 | — | — | US | disclosed |
| US-20160263258-A1 | Radiotracer introduced [18F]fluoromethyl group targeting neuroinflammation for PET imaging and Synthesis of Radiotracer and its biological evaluation Method for Radiotracer | BIO IMAGING KOREA CO., LTD. | 2016-09-15 | — | — | US | disclosed |
| CN-103608337-B | 18F-labeled precursor of PET radioactive medical supplies and preparation method thereof | FUTURECHEM株式会社 | 2016-07-06 | — | — | CN | disclosed |
| CN-105530961-A | [18f]fluoromethyl group-introduced radiotracer for positron emission tomography for targeting brain neuroinflammation, synthesis thereof, and method for evaluating biological results using same | BIO IMAGING KOREA CO LTD | 2016-04-27 | — | — | CN | disclosed |
| WO-2015037774-A1 | [18F]FLUOROMETHYL GROUP-INTRODUCED RADIOTRACER FOR POSITRON EMISSION TOMOGRAPHY FOR TARGETING BRAIN NEUROINFLAMMATION, SYNTHESIS THEREOF, AND METHOD FOR EVALUATING BIOLOGICAL RESULTS USING SAME | 주식회사 바이오이미징코리아 (KR) | 2015-03-19 | — | — | WO | disclosed |
| US-20140194620-A1 | 18F-LABELED PRECURSOR OF PET RADIOACTIVE MEDICAL SUPPLIES, AND PREPARATION METHOD THEREOF | FUTURECHEM CO., LTD. (KR) | 2014-07-10 | — | — | US | disclosed |
| US-20140194620-A1 | 18F-LABELED PRECURSOR OF PET RADIOACTIVE MEDICAL SUPPLIES, AND PREPARATION METHOD THEREOF | FUTURECHEM CO., LTD. (KR) | 2014-07-10 | — | — | US | disclosed |
| US-20140194620-A1 | 18F-LABELED PRECURSOR OF PET RADIOACTIVE MEDICAL SUPPLIES, AND PREPARATION METHOD THEREOF | FUTURECHEM CO., LTD. (KR) | 2014-07-10 | — | — | US | disclosed |
| CN-103608337-A | Of PET radioactive medical articles18F-labelled precursor and process for its preparation | UNIV SOGANG IND UNIV COOP FOUN | 2014-02-26 | — | — | CN | disclosed |
| WO-2012157900-A2 | 18F-LABELED PRECURSOR OF PET RADIOACTIVE MEDICAL SUPPLIES, AND PREPARATION METHOD THEREOF | 서강대학교산학협력단 (KR) | 2012-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160263258-A1 | Radiotracer introduced [18F]fluoromethyl group targeting neuroinflammation for PET imaging and Synthesis of Radiotracer and its biological evaluation Method for Radiotracer | TSPO, TLR8, GPR68 | CYP19A1 3087/4885NPC1 1597/4885RAB9A 683/4885 |
| US-20140194620-A1 | 18F-LABELED PRECURSOR OF PET RADIOACTIVE MEDICAL SUPPLIES, AND PREPARATION METHOD THEREOF | SLC43A1, SLC7A5, SLC35B2 | CYP19A1 1071/4885NPC1 1446/4885RAB9A 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.