Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862660 | 0.86 | UCHL1 (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7862645 | 0.86 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7865496 | 0.85 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7864997 | 0.85 | CXCR2 (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14748472 | 0.83 | UCHL1 (0.33) | — | |
| SCHEMBL19622325 | 0.82 | — | — | |
| SCHEMBL19622219 | 0.82 | CXCR2 (0.32) | — | |
| SCHEMBL7857229 | 0.82 | LIPE (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19622321 | 0.82 | — | — | |
| SCHEMBL14748438 | 0.82 | LIPE (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |