Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862660 | 0.84 | UCHL1 (0.39) | — | |
| SCHEMBL7862645 | 0.84 | PDE4A (0.38) | — | |
| SCHEMBL7864997 | 0.83 | CXCR2 (0.39) | — | |
| SCHEMBL7865496 | 0.83 | PDE4A (0.38) | LIPE | |
| SCHEMBL19622356 | 0.82 | PDE4A (0.30) | — | |
| SCHEMBL7864059 | 0.82 | PDE4A (0.36) | — | |
| SCHEMBL7865344 | 0.82 | MMP14 (0.41) | — | |
| SCHEMBL14748472 | 0.81 | UCHL1 (0.33) | — | |
| SCHEMBL19622325 | 0.81 | — | — | |
| SCHEMBL7857229 | 0.81 | LIPE (0.41) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564857-A1 | Boron-containing small molecules as anti-inflammatory agents | Anacor Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| WO-2009111676-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2009-09-11 | — | — | WO | disclosed |