Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431685 | 0.70 | CES1 (0.44) | ALDH1A1CYP2C19CES1 | |
| SCHEMBL21087587 | 0.68 | ALDH1A1 (0.43) | ALDH1A1TSHRCYP2C19NR1H2NR1H3 | |
| SCHEMBL6065415 | 0.67 | CYP2C19 (0.41) | CYP2C19KDM4ESMN1; SMN2CA2CES1 | |
| SCHEMBL10900931 | 0.66 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2C19AOC3MGLL | |
| SCHEMBL21088024 | 0.65 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2C19NR1H2NR1H3 | |
| SCHEMBL3736957 | 0.65 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP2C19NR1H2NR1H3 | |
| Iodide SCHEMBL29093986 | 0.63 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP2C19NR1H2NR1H3 | |
| SCHEMBL20740838 | 0.63 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP2C19NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL4483825 | 0.63 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP2C19NR1H2NR1H3 | |
| SCHEMBL31694265 | 0.62 | MGLL (0.65) | ALDH1A1CYP2C19NR1H2NR1H3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084166-B1 | PREPARATION PROCESS OF AROMATIC SULFONYLIMIDES | INST NAT POLYTECHNIQUE DE GRENOBLE (FR) | 2017-11-22 | — | — | EP | disclosed |