SCHEMBL21088024

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9804910	0.82	TSHR (0.52)	ALDH1A1TSHRAOC3MGLLSMN1; SMN2
	Hydrochloric Acid SCHEMBL9804592	0.80	TSHR (0.50)	ALDH1A1TSHRAOC3MGLLSMN1; SMN2
	SCHEMBL21087587	0.79	ALDH1A1 (0.43)	ALDH1A1TSHRAOC3MGLLNR1H2
	SCHEMBL10517000	0.72	TSHR (0.56)	ALDH1A1TSHRAOC3MGLLCYP2C19
	SCHEMBL21087583	0.72	TSHR (0.56)	ALDH1A1TSHRAOC3MGLLCYP2C19
	SCHEMBL28273624	0.72	TSHR (0.56)	ALDH1A1TSHRAOC3NR1H2NR1H3
	SCHEMBL4079504	0.71	ALDH1A1 (0.67)	ALDH1A1TSHRAOC3MGLLCYP2C19
	SCHEMBL23032284	0.69	ALDH1A1 (0.52)	ALDH1A1TSHRAOC3NR1H2NR1H3
	Hydrochloric Acid SCHEMBL27259243	0.69	ALDH1A1 (0.64)	ALDH1A1TSHRAOC3MGLLCYP2C19
	Chloromethane SCHEMBL28157121	0.69	TSHR (0.90)	ALDH1A1TSHRAOC3MGLLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.