Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430785 | 0.82 | CA5A (0.45) | CA5ALMNACA1CA2PKM | |
| SCHEMBL2600381 | 0.81 | CA5A (0.56) | CA5ALMNACA1CA2PKM | |
| SCHEMBL12123914 | 0.81 | CA5A (0.43) | CA5ALMNACA1CA2PKM | |
| SCHEMBL10066339 | 0.75 | CA5A (0.50) | CA5ALMNACA1CA2PKM | |
| SCHEMBL15942999 | 0.74 | CA1 (0.53) | CA5ACA1CA2PKMHPGD | |
| SCHEMBL11305809 | 0.72 | PRKCI (0.47) | CA5ALMNACA2PKMHPGD | |
| SCHEMBL12037438 | 0.71 | CYP2A6 (0.44) | LMNACA1CA2PKMHPGD | |
| SCHEMBL96069 | 0.69 | LMNA (0.59) | CA5ALMNACA1CA2HPGD | |
| SCHEMBL28160983 | 0.68 | CA5A (0.42) | CA5ALMNACA1CA2PKM | |
| SCHEMBL14450782 | 0.67 | CA5A (0.44) | CA5ALMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528604-B1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2017-11-22 | — | — | EP | disclosed |