SCHEMBL28160983

SCHEMBL28160983

CC(=O)c1cc(N)c(N=O)c(O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.42
PRKCI P41743 1/20 0.40
CREBBP Q92793 1/20 0.37
LMNA P02545 1/20 0.36
CA2 P00918 2/20 0.36
MAPT P10636 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
LIG1 P18858 1/20 0.34
PKM P14618 1/20 0.33
NOS3 P29474 2/20 0.32
NOS1 P29475 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
GCGR P47871 1/20 0.31
HDAC2 Q92769 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19670801 0.83 MAPT (0.48) CA5ALMNACA2MAPTLIG1
SCHEMBL12123914 0.79 CA5A (0.43) CA5ALMNACA2MAPTPKM
SCHEMBL27749559 0.76 CA5A (0.48) CA5APRKCICREBBPLMNACA2
SCHEMBL13846178 0.75 LMNA (0.59) CA5ALMNACA2MAPTRAB9A
SCHEMBL9400411 0.75 CYP3A4 (0.50) CA5APRKCICREBBPLMNACA2
SCHEMBL11305809 0.75 PRKCI (0.47) CA5APRKCICREBBPLMNACA2
Hydrochloric Acid SCHEMBL18317014 0.73 ALDH1A1 (0.42) LMNAMAPTNPC1LIG1PKM
SCHEMBL14450782 0.70 CA5A (0.44) CA5ALMNAMAPTNPC1RAB9A
SCHEMBL6430785 0.69 CA5A (0.45) CA5ALMNACA2MAPTNPC1
SCHEMBL11027202 0.69 PRKCI (0.48) CA5APRKCICREBBPLMNACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106928160-A A kind of preparation method of cresol-purple perchlorate 大连九信精细化工有限公司 2017-07-07 CN claimed