Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19533678 | 0.90 | MAPT (0.50) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL19545219 | 0.87 | MAPT (0.47) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL27321802 | 0.80 | RAB9A (0.63) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL19533676 | 0.79 | MAPT (0.62) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL5317300 | 0.75 | HDAC6 (0.54) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL593327 | 0.73 | KDM4E (0.58) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL2838238 | 0.73 | ALDH1A1 (0.54) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL5937229 | 0.72 | ALDH1A1 (0.53) | MAPTSMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL25060404 | 0.72 | MAPT (0.49) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL19624943 | 0.72 | ALDH1A1 (0.53) | MAPTSMN1; SMN2RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |