Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544677 | 0.90 | PTGS2 (0.48) | ALDH1A1MAPTPTGS2KDM4EHPGDS | |
| SCHEMBL19624842 | 0.84 | HPGDS (0.51) | ALDH1A1MAPTKDM4ERAB9AHPGDS | |
| SCHEMBL27321802 | 0.82 | RAB9A (0.63) | ALDH1A1MAPTKDM4ERAB9AHPGDS | |
| SCHEMBL19544670 | 0.79 | MAPT (0.66) | ALDH1A1MAPTPTGS2RAB9AHPGDS | |
| SCHEMBL5349967 | 0.78 | PTGS2 (0.60) | ALDH1A1MAPTPTGS2RAB9APOLB | |
| SCHEMBL19533569 | 0.77 | DHODH (0.41) | ALDH1A1MAPTPTGS2RAB9ASCN9A | |
| SCHEMBL5317300 | 0.77 | HDAC6 (0.54) | ALDH1A1MAPTPTGS2KDM4ERAB9A | |
| SCHEMBL19624845 | 0.77 | MAPT (0.54) | ALDH1A1MAPTKDM4ERAB9AHPGDS | |
| SCHEMBL19544658 | 0.76 | SCN9A (0.54) | ALDH1A1MAPTPTGS2KDM4ERAB9A | |
| SCHEMBL19533659 | 0.75 | HPGDS (0.48) | ALDH1A1MAPTKDM4ERAB9AHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |